Evidence map›Paper›PMID 28559404›Full record

ArticleInfection and immunity2017

Peripheral T-Cell Reactivity to Heat Shock Protein 70 and Its Cofactor GrpE from Tropheryma whipplei Is Reduced in Patients with Classical Whipple's Disease.

Lucia Trotta, Kathleen Weigt, Katina Schinnerling, Anika Geelhaar-Karsch, Gerrit Oelkers, Federico Biagi, Gino Roberto Corazza, Kristina Allers, Thomas Schneider, Ulrike Erben and 1 more

Open access · bronzeAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Infection and immunity, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.6field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 2 institutions in 2 countries.

Lucia TrottaFirst Department of Internal Medicine, University of Pavia, IRCCS Policlinico San Matteo, Pavia, Italy.
Kathleen WeigtMedical Department for Gastroenterology, Infectious Diseases and Rheumatology, Charité-Universitätsmedizin Berlin, CBF, Berlin, Germany.
Katina SchinnerlingMedical Department for Gastroenterology, Infectious Diseases and Rheumatology, Charité-Universitätsmedizin Berlin, CBF, Berlin, Germany.
Anika Geelhaar-KarschMedical Department for Gastroenterology, Infectious Diseases and Rheumatology, Charité-Universitätsmedizin Berlin, CBF, Berlin, Germany.
Gerrit OelkersMedical Department for Gastroenterology, Infectious Diseases and Rheumatology, Charité-Universitätsmedizin Berlin, CBF, Berlin, Germany.
Federico BiagiFirst Department of Internal Medicine, University of Pavia, IRCCS Policlinico San Matteo, Pavia, Italy.
Gino Roberto CorazzaFirst Department of Internal Medicine, University of Pavia, IRCCS Policlinico San Matteo, Pavia, Italy.
Kristina AllersMedical Department for Gastroenterology, Infectious Diseases and Rheumatology, Charité-Universitätsmedizin Berlin, CBF, Berlin, Germany.
Thomas SchneiderMedical Department for Gastroenterology, Infectious Diseases and Rheumatology, Charité-Universitätsmedizin Berlin, CBF, Berlin, Germany.
Ulrike ErbenMedical Department for Gastroenterology, Infectious Diseases and Rheumatology, Charité-Universitätsmedizin Berlin, CBF, Berlin, Germany.
Verena MoosMedical Department for Gastroenterology, Infectious Diseases and Rheumatology, Charité-Universitätsmedizin Berlin, CBF, Berlin, Germany verena.moos@charite.de.ORCID http://orcid.org/0000-0002-9558-7291
Charité - Universitätsmedizin Berlin · DEUniversity of Pavia · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Classical Whipple's disease (CWD) is characterized by the lack of specific Th1 response toward

Indexed as

AdultAgedAged, 80 and overAntigens, CDBacterial ProteinsB-LymphocytesCD4-Positive T-LymphocytesCD8-Positive T-LymphocytesDuodenumFemaleFlow CytometryHeat-Shock ProteinsHSP70 Heat-Shock ProteinsHumansInterferon-gammaIntestinal MucosaAntigens, CDBacterial ProteinsGrpE protein, BacteriaHeat-Shock ProteinsHSP70 Heat-Shock ProteinsInterferon-gammacofactor GrpEheat-shock protein 70T-cell immunityTropheryma whippleiWhipple's disease

Identifiers

PMID28559404
PMCPMC5520441
OpenAlexW2618720156

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.