ArticleThe Journal of neuroscience : the official journal of the Society for Neuroscience2017
Axonal Conduction Delays, Brain State, and Corticogeniculate Communication.
Article in The Journal of neuroscience : the official journal of the Society for Neuroscience, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
28 citing papers in PubMed.
- Neuronal dynamics, timing, and flow of sensory and choice-related information in auditory-prefrontal circuitry.Nature communications · 2026Article
- Fast-Spike Interneurons in Visual Cortical Layer 5: Heterogeneous Response Properties Are Related to Thalamocortical Connectivity.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2025Article
- Time delays in computational models of neuronal and synaptic dynamics.Frontiers in computational neuroscience · 2025Article
- Adapting to time: Why nature may have evolved a diverse set of neurons.PLoS computational biology · 2024Article
- Article
- Motor Control of Distinct Layer 6 Corticothalamic Feedback Circuits.bioRxiv : the preprint server for biology · 2024Article
- Visual Corticotectal Neurons in Awake Rabbits: Receptive Fields and Driving Monosynaptic Thalamocortical Inputs.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2024Article
- Delay-dependent transitions of phase synchronization and coupling symmetry between neurons shaped by spike-timing-dependent plasticity.Cognitive neurodynamics · 2023Article
- Brain State-Dependent Modulation of Thalamic Visual Processing by Cortico-Thalamic Feedback.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2023Article
- Decoupling of interacting neuronal populations by time-shifted stimulation through spike-timing-dependent plasticity.PLoS computational biology · 2023Article
- Learnable axonal delay in spiking neural networks improves spoken word recognition.Frontiers in neuroscience · 2023Article
- Robust effects of corticothalamic feedback and behavioral state on movie responses in mouse dLGN.eLife · 2022Article
- Article
- Distinct "driving" versus "modulatory" influences of different visual corticothalamic pathways.Current biology : CB · 2021Article
- The synaptic inputs and thalamic projections of two classes of layer 6 corticothalamic neurons in primary somatosensory cortex of the mouse.The Journal of comparative neurology · 2021Article
- Article
- Role of NMDAR plasticity in a computational model of synaptic memory.Scientific reports · 2021Article
- Untangling the cortico-thalamo-cortical loop: cellular pieces of a knotty circuit puzzle.Nature reviews. Neuroscience · 2021Review
- A Closer Look at Corticothalamic "Loops".Frontiers in neural circuits · 2021Article
- Role of Feedback Connections in Central Visual Processing.Annual review of vision science · 2020Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
Abstract
Thalamocortical conduction times are short, but layer 6 corticothalamic axons display an enormous range of conduction times, some exceeding 40-50 ms. Here, we investigate (1) how axonal conduction times of corticogeniculate (CG) neurons are related to the visual information conveyed to the thalamus, and (2) how alert versus nonalert awake brain states affect visual processing across the spectrum of CG conduction times. In awake female Dutch-Belted rabbits, we found 58% of CG neurons to be visually responsive, and 42% to be unresponsive. All responsive CG neurons had simple, orientation-selective receptive fields, and generated sustained responses to stationary stimuli. CG axonal conduction times were strongly related to modulated firing rates (F1 values) generated by drifting grating stimuli, and their associated interspike interval distributions, suggesting a continuum of visual responsiveness spanning the spectrum of axonal conduction times. CG conduction times were also significantly related to visual response latency, contrast sensitivity (C-50 values), directional selectivity, and optimal stimulus velocity. Increasing alertness did not cause visually unresponsive CG neurons to become responsive and did not change the response linearity (F1/F0 ratios) of visually responsive CG neurons. However, for visually responsive CG neurons, increased alertness nearly doubled the modulated response amplitude to optimal visual stimulation (F1 values), significantly shortened response latency, and dramatically increased response reliability. These effects of alertness were uniform across the broad spectrum of CG axonal conduction times.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.