ArticleThe Journal of neuroscience : the official journal of the Society for Neuroscience2017
Stable and Dynamic Coding for Working Memory in Primate Prefrontal Cortex.
Article in The Journal of neuroscience : the official journal of the Society for Neuroscience, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 117 papers, 1 of them a synthesis that pooled it.
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Who cites it
117 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Identifying regions in prefrontal cortex related to working memory improvement: A novel meta-analytic method using electric field modeling.Neuroscience and biobehavioral reviews · 2021Pooled it
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- Sensorimotor transformation of number in the primate parietal cortex.Nature communications · 2026Article
- Dopamine D1 and D2 receptors differentially control strength and dynamics of abstract decision codes in the primate prefrontal cortex.Proceedings of the National Academy of Sciences of the United States of America · 2026Article
- Slow-wave sleep and REM sleep differentially contribute to memory representational transformation.Communications biology · 2025Article
- Causal role for pulvinar burst firing in thalamo-cortical attention control.bioRxiv : the preprint server for biology · 2025Article
- Encoding of visual stimuli and behavioral goals in distinct anatomical areas of monkey ventrolateral prefrontal cortex.PLoS biology · 2025Article
- Out of the single-neuron straitjacket: Neurons within assemblies change selectivity and their reconfiguration underlies dynamic coding.The Journal of physiology · 2025Article
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- Neural correlates of memory updating in the primate prefrontal cortex.Communications biology · 2025Article
- Medium Spiny Neurons Mediate Timing Perception in Coordination with Prefrontal Neurons in Primates.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025Article
- Mixed recurrent connectivity in primate prefrontal cortex.PLoS computational biology · 2025Article
- Compositional architecture: Orthogonal neural codes for task context and spatial memory in prefrontal cortex.bioRxiv : the preprint server for biology · 2025Article
- Ramping dynamics in the frontal cortex unfold over multiple timescales during motor planning.Journal of neurophysiology · 2025Article
- Exploring imitation of within hand prehensile object manipulation using fMRI and graph theory analysis.Scientific reports · 2025Article
- Cognitive network interactions through communication subspaces in large-scale models of the neocortex.bioRxiv : the preprint server for biology · 2024Article
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- A gradual transition toward categorical representations along the visual hierarchy during working memory, but not perception.bioRxiv : the preprint server for biology · 2024Article
57 more citing papers are in PubMed but not listed here.
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4 authors.
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Abstract
Working memory (WM) provides the stability necessary for high-level cognition. Influential theories typically assume that WM depends on the persistence of stable neural representations, yet increasing evidence suggests that neural states are highly dynamic. Here we apply multivariate pattern analysis to explore the population dynamics in primate lateral prefrontal cortex (PFC) during three variants of the classic memory-guided saccade task (recorded in four animals). We observed the hallmark of dynamic population coding across key phases of a working memory task: sensory processing, memory encoding, and response execution. Throughout both these dynamic epochs and the memory delay period, however, the neural representational geometry remained stable. We identified two characteristics that jointly explain these dynamics: (1) time-varying changes in the subpopulation of neurons coding for task variables (i.e., dynamic subpopulations); and (2) time-varying selectivity within neurons (i.e., dynamic selectivity). These results indicate that even in a very simple memory-guided saccade task, PFC neurons display complex dynamics to support stable representations for WM.
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