Evidence map›Paper›PMID 28559332›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2017

Rifamycin action on RNA polymerase in antibiotic-tolerant

Kohta Saito, Thulasi Warrier, Selin Somersan-Karakaya, Lina Kaminski, Jianjie Mi, Xiuju Jiang, Suna Park, Kristi Shigyo, Ben Gold, Julia Roberts and 3 more

Open access · bronzeAbstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 56 papers.

0numbers the graph read from it
0cells of the map it votes in
56citing papers in PubMed
4.4field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

56 citing papers in PubMed, 93 citations in OpenAlex.

  1. MakingCell insight · 2026
    Review
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  3. Article
  4. Review
  5. Reactive Oxygen Detoxification Contributes tobioRxiv : the preprint server for biology · 2025
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  12. High variance in quantification ofAntimicrobial agents and chemotherapy · 2024
    Article
  13. Clinical Strains ofPathogens (Basel, Switzerland) · 2024
    Article
  14. Article
  15. Article
  16. Article
  17. Culture-negative TB: clinical characteristics, risk factors and treatment outcomes.The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease · 2023
    Article
  18. A tRNA modification inbioRxiv : the preprint server for biology · 2023
    Article
  19. Eradication of Drug-TolerantMicroorganisms · 2023
    Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 4 institutions in 1 country.

Kohta SaitoDepartment of Microbiology and Immunology, Weill Cornell Medicine, New York, NY 10065.
Thulasi WarrierDepartment of Microbiology and Immunology, Weill Cornell Medicine, New York, NY 10065.
Selin Somersan-KarakayaDepartment of Medicine, Weill Cornell Medicine, New York, NY 10065.
Lina KaminskiDepartment of Microbiology and Immunology, Albert Einstein College of Medicine, Bronx, NY 10461.
Jianjie MiDepartment of Microbiology and Immunology, Weill Cornell Medicine, New York, NY 10065.
Xiuju JiangDepartment of Microbiology and Immunology, Weill Cornell Medicine, New York, NY 10065.
Suna ParkDepartment of Microbiology and Immunology, Weill Cornell Medicine, New York, NY 10065.
Kristi ShigyoDepartment of Microbiology and Immunology, Weill Cornell Medicine, New York, NY 10065.
Ben GoldDepartment of Microbiology and Immunology, Weill Cornell Medicine, New York, NY 10065.
Julia RobertsDepartment of Microbiology and Immunology, Weill Cornell Medicine, New York, NY 10065.
Elaina WeberDepartment of Microbiology and Immunology, Weill Cornell Medicine, New York, NY 10065.
William R JacobsDepartment of Microbiology and Immunology, Albert Einstein College of Medicine, Bronx, NY 10461.
Carl F NathanDepartment of Microbiology and Immunology, Weill Cornell Medicine, New York, NY 10065; cnathan@med.cornell.edu.
Weill Cornell Medicine · USCornell University · USAlbert Einstein College of Medicine · USHoward Hughes Medical Institute · US

Funding

X-RAY CRYSTALLOGRAPHYP30CA008748 · NCI · SLOAN-KETTERING INSTITUTE FOR CANCER RES · PI Nicholas D Socci · 1985 to 2026
$347.4M
Viable but Nonculturable MtbU19AI111143 · NIAID · WEILL MEDICAL COLL OF CORNELL UNIV · PI GLICKMAN, MICHAEL S, NATHAN, CARL FRANCIS · 2014 to 2020
$48.6M
Validation and Application of a Model for Human-like TB Latency in RabbitsU19AI111276 · NIAID · RBHS-NEW JERSEY MEDICAL SCHOOL · PI ALLAND, DAVID, HORN, DAVID LOUIS · 2014 to 2020
$23.3M
T32: Pathogenesis of Infectious Diseases Training ProgramT32AI007613 · NIAID · WEILL MEDICAL COLL OF CORNELL UNIV · PI ROY M. GULICK · 1999 to 2026
$8.8M
Molecular Genetic Analysis of Mycobacterium TuberculosisR37AI026170 · NIAID · ALBERT EINSTEIN COL OF MED YESHIVA UNIV · PI WILLIAM Robert JACOBS · 2004 to 2026
$7.7M
MOLECULAR GENETIC ANALYSIS OF MYCOBACTERIUM TUBERCULOSISR01AI026170 · NIAID · YESHIVA UNIVERSITY · PI JACOBS, WILLIAM ROBERT · 1989 to 2022
$7.1M
Calanolides as tools to find new drug targets for Mycobacterium tuberculosisK08AI108799 · NIAID · WEILL MEDICAL COLL OF CORNELL UNIV · PI SOMERSAN-KARAKAYA, SELIN S · 2014 to 2018
$921k
Howard Hughes Medical InstituteNCI NIH HHS P30 CA008748NIAID NIH HHS K08 AI108799NIAID NIH HHS R01 AI026170NIAID NIH HHS R37 AI026170NIAID NIH HHS T32 AI007613NIAID NIH HHS U19 AI111143NIAID NIH HHS U19 AI111276
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Antibiotics, AntitubercularAntitubercular AgentsBacterial ProteinsDNA-Directed RNA PolymerasesDrug Resistance, BacterialHumansIsoniazidMutationMycobacterium tuberculosisRifamycinsThioridazineTuberculosisAntibiotics, AntitubercularAntitubercular AgentsBacterial ProteinsDNA-Directed RNA PolymerasesIsoniazidRifamycinsRNA polymerase beta subunitrpoB protein, Mycobacterium tuberculosisThioridazinedifferentially detectableMycobacterium tuberculosisphenotypic tolerancerifampinthioridazine

Identifiers

PMID28559332
PMCPMC5474769
OpenAlexW2619419024

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.