Evidence map›Paper›PMID 28559283›Full record

ArticleThe Journal of biological chemistry2017

Molecular dynamics simulations reveal the conformational dynamics of

Alexander S Moffett, Kyle W Bender, Steven C Huber, Diwakar Shukla

Open access · hybridAbstract read
In one paragraph

Article in The Journal of biological chemistry, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
2.9field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 60 citations in OpenAlex.

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  6. Activation loop phosphorylation of a non-RD receptor kinase initiates plant innate immune signaling.Proceedings of the National Academy of Sciences of the United States of America · 2021
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Alexander S MoffettCenter for Biophysics and Quantitative Biology, University of Illinois, Urbana, Illinois 61801.
Kyle W BenderDepartment of Plant Biology, University of Illinois, Urbana, Illinois 61801.
Steven C HuberDepartment of Plant Biology, University of Illinois, Urbana, Illinois 61801; Global Change and Photosynthesis Research Unit, United States Department of Agriculture-Agricultural Research Service, Urbana, Illinois 61801.
Diwakar ShuklaCenter for Biophysics and Quantitative Biology, University of Illinois, Urbana, Illinois 61801; Department of Plant Biology, University of Illinois, Urbana, Illinois 61801; Department of Chemical and Biomolecular Engineering, University of Illinois, Urbana, Illinois 61801. Electronic address: diwakar@illinois.edu.
University of Illinois Urbana-Champaign · USAgricultural Research Service · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The structural motifs responsible for activation and regulation of eukaryotic protein kinases in animals have been studied extensively in recent years, and a coherent picture of their activation mechanisms has begun to emerge. In contrast, non-animal eukaryotic protein kinases are not as well understood from a structural perspective, representing a large knowledge gap. To this end, we investigated the conformational dynamics of two key

Indexed as

Molecular Dynamics SimulationArabidopsisArabidopsis ProteinsProtein ConformationProtein KinasesProtein Serine-Threonine KinasesArabidopsis ProteinsBAK1 protein, ArabidopsisBRI1 protein, ArabidopsisProtein KinasesProtein Serine-Threonine KinasesBAK1BRI1conformational changeMarkov state modelsmolecular dynamicsplant molecular biologyprotein kinasesignal transduction

Identifiers

PMID28559283
PMCPMC5535038
OpenAlexW2619232669

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.