Evidence map›Paper›PMID 28559281›Full record

ArticleThe Journal of biological chemistry2017

Uridine monophosphate synthetase enables eukaryotic

Melanie R McReynolds, Wenqing Wang, Lauren M Holleran, Wendy Hanna-Rose

Open access · hybridAbstract read
In one paragraph

Article in The Journal of biological chemistry, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
0.8field-weighted citation impact, top 34% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 23 citations in OpenAlex.

  1. Review
  2. Review
  3. De novo NADCommunications biology · 2025
    Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Effects of NADBiomolecules · 2020
    Review
  9. BCL-2 family protein BOK is a positive regulator of uridine metabolism in mammals.Proceedings of the National Academy of Sciences of the United States of America · 2019
    Article
  10. Article
  11. Review
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Melanie R McReynoldsFrom the Department of Biochemistry and Molecular Biology, The Pennsylvania State University, University Park, Pennsylvania 16802.
Wenqing WangFrom the Department of Biochemistry and Molecular Biology, The Pennsylvania State University, University Park, Pennsylvania 16802.
Lauren M HolleranFrom the Department of Biochemistry and Molecular Biology, The Pennsylvania State University, University Park, Pennsylvania 16802.
Wendy Hanna-RoseFrom the Department of Biochemistry and Molecular Biology, The Pennsylvania State University, University Park, Pennsylvania 16802 wxh21@psu.edu.ORCID 0000-0002-5566-4758
Pennsylvania State University · US

Funding

Enhancing and expanding the CGC Strain CollectionP40OD010440 · OD · UNIVERSITY OF MINNESOTA · PI Aric L Daul, Ann E. Rougvie · 2012 to 2026
$7.5M
Probing functions of NAM and NAD+ salvage in development and aging in C. elegansR01GM086786 · NIGMS · PENNSYLVANIA STATE UNIVERSITY, THE · PI HANNA-ROSE, WENDY · 2009 to 2013
$1.7M
NIGMS NIH HHS R01 GM086786NIH HHS P40 OD010440
6 · The paper itself

Abstract

NAD

Indexed as

Caenorhabditis elegansCaenorhabditis elegans ProteinsMultienzyme ComplexesNADOrotate PhosphoribosyltransferaseOrotidine-5'-Phosphate DecarboxylaseAnimalsMutationQuinolinic AcidTryptophanCaenorhabditis elegans ProteinsMultienzyme ComplexesNADOrotate PhosphoribosyltransferaseOrotidine-5'-Phosphate DecarboxylaseQuinolinic AcidTryptophanuridine 5'-monophosphate synthaseCaenorhabditis elegans (C. elegans)metabolic tracermetabolismNAD biosynthesistryptophan

Identifiers

PMID28559281
PMCPMC5500784
OpenAlexW2617221282

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.