Evidence map›Paper›PMID 28559275›Full record

ArticleAntimicrobial agents and chemotherapy2017

Urinary Concentrations of Colistimethate and Formed Colistin after Intravenous Administration in Patients with Multidrug-Resistant Gram-Negative Bacterial Infections.

Sonia Luque, Carol Escaño, Luisa Sorli, Jian Li, Nuria Campillo, Juan Pablo Horcajada, Esther Salas, Santiago Grau

Open access · bronzeAbstract read
In one paragraph

Article in Antimicrobial agents and chemotherapy, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 1 pooled it
1.1field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 1 synthesis or guideline pooled it, 23 citations in OpenAlex.

  1. Guideline
  2. Article
  3. Article
  4. Article
  5. Observational
  6. Review
  7. Article
  8. Review
  9. Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 2 countries.

Sonia LuquePharmacy Department, Hospital del Mar, Barcelona, Spain sluque@parcdesalutmar.cat.
Carol EscañoInfectious Diseases Department, Hospital del Mar, Barcelona, Spain.
Luisa SorliInstitut Hospital del Mar d'Investigacions Mèdiques (IMIM), Barcelona, Spain.
Jian LiMonash Biomedicine Discovery Institute and Department of Microbiology, Monash University, Victoria, Australia.
Nuria CampilloPharmacy Department, Hospital del Mar, Barcelona, Spain.
Juan Pablo HorcajadaInstitut Hospital del Mar d'Investigacions Mèdiques (IMIM), Barcelona, Spain.
Esther SalasPharmacy Department, Hospital del Mar, Barcelona, Spain.
Santiago GrauPharmacy Department, Hospital del Mar, Barcelona, Spain.
Hospital Del Mar · ESHospital del Mar Research Institute · ESMonash University · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Limited information is available on the urinary excretion of colistin in infected patients. This study aimed to investigate the pharmacokinetics of colistimethate sodium (CMS) and formed colistin in urine in patients with multidrug-resistant (MDR) Gram-negative bacterial infections. A pharmacokinetic study was conducted on 12 patients diagnosed with an infection caused by an extremely drug-resistant (XDR)

Indexed as

Acinetobacter baumanniiAcinetobacter InfectionsAdultAgedAged, 80 and overAnti-Bacterial AgentsChromatography, High Pressure LiquidColistinDrug Resistance, Multiple, BacterialFemaleHumansInfusions, IntravenousMaleMiddle AgedProspective StudiesPseudomonas aeruginosaAnti-Bacterial AgentsColistincolistinmethanesulfonic acidcolistinGram-negative bacteriapharmacokineticsurinary tract infections

Identifiers

PMID28559275
PMCPMC5527601
OpenAlexW2617124917

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.