Evidence map›Paper›PMID 28559266›Full record

ArticleAntimicrobial agents and chemotherapy2017

An Immunomodulatory Peptide Confers Protection in an Experimental Candidemia Murine Model.

Camila G Freitas, Stella M F Lima, Mirna S Freire, Ana Paula C Cantuária, Nelson G O Júnior, Tatiane S Santos, Jéssica S Folha, Suzana M Ribeiro, Simoni C Dias, Taia M B Rezende and 6 more

Open access · bronzeAbstract read
In one paragraph

Article in Antimicrobial agents and chemotherapy, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
1.9field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 26 citations in OpenAlex.

  1. Mini reviews in medicinal chemistry · 2025
    Review
  2. Review
  3. Article
  4. The future of recombinant host defense peptides.Microbial cell factories · 2022
    Review
  5. Review
  6. Article
  7. Review
  8. Host Defense Peptides as Templates for Antifungal Drug Development.Journal of fungi (Basel, Switzerland) · 2020
    Review
  9. Article
  10. Review
  11. Article
  12. Review
  13. Review
  14. Review
  15. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors at 5 institutions in 3 countries.

Camila G FreitasCentro de Análises Proteômicas e Bioquímicas, Brasília, Distrito Federal, Brazil.ORCID 0000-0003-0617-3220
Stella M F LimaCentro de Análises Proteômicas e Bioquímicas, Brasília, Distrito Federal, Brazil.
Mirna S FreireCentro de Análises Proteômicas e Bioquímicas, Brasília, Distrito Federal, Brazil.
Ana Paula C CantuáriaCentro de Análises Proteômicas e Bioquímicas, Brasília, Distrito Federal, Brazil.
Nelson G O JúniorCentro de Análises Proteômicas e Bioquímicas, Brasília, Distrito Federal, Brazil.
Tatiane S SantosUniversidade de Brasília, Brasília, Brazil.
Jéssica S FolhaUniversidade de Brasília, Brasília, Brazil.
Suzana M RibeiroCentro de Análises Proteômicas e Bioquímicas, Brasília, Distrito Federal, Brazil.
Simoni C DiasCentro de Análises Proteômicas e Bioquímicas, Brasília, Distrito Federal, Brazil.
Taia M B RezendeCentro de Análises Proteômicas e Bioquímicas, Brasília, Distrito Federal, Brazil.
Patrícia AlbuquerqueUniversidade de Brasília, Brasília, Brazil.
André M NicolaPrograma de Pós-Graduação em Ciências Genômicas e Biotecnologia, Universidade Católica de Brasília, Brasília, Brazil.
César de la Fuente-NúñezSynthetic Biology Group, MIT Synthetic Biology Center, Massachusetts Institute of Technology, Cambridge, Massachusetts, USA.
Robert E W HancockCenter for Microbial Diseases and Immunity Research, Department of Microbiology and Immunology, University of British Columbia, Vancouver, British Columbia, Canada.
Octávio L FrancoCentro de Análises Proteômicas e Bioquímicas, Brasília, Distrito Federal, Brazil ocfranco@gmail.com.
Maria Sueli S FelipeCentro de Análises Proteômicas e Bioquímicas, Brasília, Distrito Federal, Brazil.
Universidade de Brasília · BRUniversidade Católica de Brasília · BRBroad Institute · USUniversidade Católica Dom Bosco · BRUniversity of British Columbia · CA

Funding

CIHR
6 · The paper itself

Abstract

Fungal

Indexed as

AnimalsAntifungal AgentsAntimicrobial Cationic PeptidesBiofilmsCandida albicansCandidemiaCell LineChemokine CCL2Disease Models, AnimalImmunologic FactorsInterleukin-10Interleukin-12 Subunit p35Interleukin-1betaInterleukin-6MacrophagesMiceAntifungal AgentsAntimicrobial Cationic PeptidesCcl2 protein, mouseChemokine CCL2IL10 protein, mouseIl12a protein, mouseIL1B protein, mouseImmunologic Factorsinnate defense regulating peptide 1018Interleukin-10Interleukin-12 Subunit p35Interleukin-1betaInterleukin-6interleukin-6, mouseTumor Necrosis Factor-alphaantifungalsCandida albicanshost-directed therapyIDR-1018 peptideimmunomodulatory effectsmurine experimental candidemia

Identifiers

PMID28559266
PMCPMC5527641
OpenAlexW2617456826

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.