Evidence map›Paper›PMID 28559263›Full record

ArticleAntimicrobial agents and chemotherapy2017

Efficient Killing of Planktonic and Biofilm-Embedded Coagulase-Negative Staphylococci by Bactericidal Protein P128.

Nethravathi Poonacha, Sandhya Nair, Srividya Desai, Darshan Tuppad, Deepika Hiremath, Thulasi Mohan, Aradhana Vipra, Umender Sharma

Open access · bronzeAbstract read
In one paragraph

Article in Antimicrobial agents and chemotherapy, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed
2.8field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 48 citations in OpenAlex.

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  5. International journal of molecular sciences · 2023
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  19. Frontiers in microbiology · 2020
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Nethravathi PoonachaGangaGen Biotechnologies Pvt Ltd., Yeshwantpur, Bangalore, India.
Sandhya NairGangaGen Biotechnologies Pvt Ltd., Yeshwantpur, Bangalore, India.
Srividya DesaiGangaGen Biotechnologies Pvt Ltd., Yeshwantpur, Bangalore, India.
Darshan TuppadGangaGen Biotechnologies Pvt Ltd., Yeshwantpur, Bangalore, India.
Deepika HiremathGangaGen Biotechnologies Pvt Ltd., Yeshwantpur, Bangalore, India.
Thulasi MohanGangaGen Biotechnologies Pvt Ltd., Yeshwantpur, Bangalore, India.
Aradhana VipraGangaGen Biotechnologies Pvt Ltd., Yeshwantpur, Bangalore, India.
Umender SharmaGangaGen Biotechnologies Pvt Ltd., Yeshwantpur, Bangalore, India umender@gangagen.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Coagulase-negative staphylococci (CoNS) are the major causative agents of foreign-body-related infections, including catheter-related bloodstream infections. Because of the involvement of biofilms, foreign-body-related infections are difficult to treat. P128, a chimeric recombinant phage-derived ectolysin, has been shown to possess bactericidal activity on strains of

Indexed as

Anti-Bacterial AgentsBiofilmsCatheter-Related InfectionsCoagulaseDaptomycinDrug SynergismDrug Therapy, CombinationForeign-Body ReactionHumansMicrobial Sensitivity TestsRecombinant Fusion ProteinsStaphylococcal InfectionsStaphylococcus epidermidisStaphylococcus haemolyticusStaphylococcus lugdunensisVancomycinAnti-Bacterial AgentsCoagulaseDaptomycinP128 antistaphylococcal chimeric proteinRecombinant Fusion ProteinsVancomycinbiofilmscatheter-related infectionscoagulase-negative staphylococciCoNSCRBSIforeign-body-related infectionsP128persistersstationary phasesynergy

Identifiers

PMID28559263
PMCPMC5527639
OpenAlexW2616992910

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.