ArticleFungal genetics and biology : FG & B2017
Real-time visualization of immune cell clearance of Aspergillus fumigatus spores and hyphae.
Article in Fungal genetics and biology : FG & B, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
20 citing papers in PubMed, 26 citations in OpenAlex.
- Molecular mechanisms drivingFrontiers in molecular biosciences · 2026Review
- Zebrafish (International journal of molecular sciences · 2024Review
- Glucocorticoids Suppress NF-κB-Mediated Neutrophil Control of Aspergillus fumigatus Hyphal Growth.Journal of immunology (Baltimore, Md. : 1950) · 2024Article
- Stimulating the autophagic-lysosomal axis enhances host defense against fungal infection in a zebrafish model of invasive Aspergillosis.Autophagy · 2023Article
- Novel Insights intoJournal of fungi (Basel, Switzerland) · 2022Review
- Invasive Pulmonary Aspergillosis with Marked Eosinophilia as a Unique Presentation of Chronic Granulomatous Disease.European journal of case reports in internal medicine · 2022Article
- Guide to the Larval Zebrafish-Aspergillus Infection Model.Current protocols · 2021Article
- Dynamic optimization reveals alveolar epithelial cells as key mediators of host defense in invasive aspergillosis.PLoS computational biology · 2021Article
- Review
- Infection of Zebrafish Larvae with Aspergillus Spores for Analysis of Host-Pathogen Interactions.Journal of visualized experiments : JoVE · 2020Article
- Pathogenicity and Immune Responses ofFrontiers in veterinary science · 2020Article
- Neutrophil phagocyte oxidase activity controls invasive fungal growth and inflammation in zebrafish.Journal of cell science · 2019Article
- β-glucan-dependent shuttling of conidia from neutrophils to macrophages occurs during fungal infection establishment.PLoS biology · 2019Article
- Early Interaction of Alternaria infectoria Conidia with Macrophages.Mycopathologia · 2019Article
- The Zebrafish as a Model Host for Invasive Fungal Infections.Journal of fungi (Basel, Switzerland) · 2018Review
- Macrophages inhibit Aspergillus fumigatus germination and neutrophil-mediated fungal killing.PLoS pathogens · 2018Article
- Macrophages protect Talaromyces marneffei conidia from myeloperoxidase-dependent neutrophil fungicidal activity during infection establishment in vivo.PLoS pathogens · 2018Article
- Article
- Defective calcineurin/NFAT signaling in myeloid cells and susceptibility to aspergillosis in post-transplant patients.Virulence · 2017Article
- Macrophage-Microbe Interactions: Lessons from the Zebrafish Model.Frontiers in immunology · 2017Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 1 institution in 1 country.
Funding
Abstract
Invasive aspergillosis (IA) is a disease of the immunocompromised host and generally caused by the opportunistic fungal pathogen Aspergillus fumigatus. While both host and fungal factors contribute to disease severity and outcome, there are fundamental features of IA development including fungal morphological transition from infectious conidia to tissue-penetrating hyphae as well as host defenses rooted in mechanisms of innate phagocyte function. Here we address recent advances in the field and use real-time in vivo imaging in the larval zebrafish to visually highlight conserved vertebrate innate immune behaviors including macrophage phagocytosis of conidia and neutrophil responses post-germination.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.