Evidence map›Paper›PMID 28559070›Full record

ArticleWorld neurosurgery2017

Severe Traumatic Brain Injury at a Tertiary Referral Center in Tanzania: Epidemiology and Adherence to Brain Trauma Foundation Guidelines.

Luke R Smart, Halinder S Mangat, Benson Issarow, Paul McClelland, Gerald Mayaya, Emmanuel Kanumba, Linda M Gerber, Xian Wu, Robert N Peck, Isidore Ngayomela and 3 more

Open access · greenAbstract read
In one paragraph

Article in World neurosurgery, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
2.8field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 47 citations in OpenAlex.

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  8. Burr hole as a management for extra axial hematomas in a low-resource setting.International journal of surgery case reports · 2023
    Article
  9. Article
  10. Injury characteristics and their association with clinical complications among emergency care patients in Tanzania.African journal of emergency medicine : Revue africaine de la medecine d'urgence · 2022
    Article
  11. Article
  12. Review
  13. Article
  14. Article
  15. Article
  16. Access to the Intensive Care Unit by Severe Head Injury Patients.Journal of neurosciences in rural practice · 2019
    Article
  17. Review
  18. Observational
  19. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 2 institutions in 2 countries.

Luke R SmartDepartment of Internal Medicine, Weill Bugando School of Medicine, Mwanza, Tanzania; Center for Global Health, Weill Cornell Medicine, New York, New York, USA.
Halinder S MangatDepartment of Neurology, Weill Cornell Medicine, New York, New York, USA; Weill Cornell Brain and Spine Center, Department of Neurological Surgery, Weill Cornell Medicine, New York, New York, USA. Electronic address: hsm9001@med.cornell.edu.
Benson IssarowWeill Bugando School of Medicine, Mwanza, Tanzania.
Paul McClellandCenter for Global Health, Weill Cornell Medicine, New York, New York, USA.
Gerald MayayaDepartment of Neurosurgery, Bugando Medical Centre, Mwanza, Tanzania.
Emmanuel KanumbaDepartment of Neurosurgery, Bugando Medical Centre, Mwanza, Tanzania.
Linda M GerberDepartment of Healthcare Policy & Research, Weill Cornell Medicine, New York, New York, USA.
Xian WuDepartment of Healthcare Policy & Research, Weill Cornell Medicine, New York, New York, USA.
Robert N PeckDepartment of Internal Medicine, Weill Bugando School of Medicine, Mwanza, Tanzania; Center for Global Health, Weill Cornell Medicine, New York, New York, USA.
Isidore NgayomelaDepartment of Orthopedic Surgery, Bugando Medical Centre, Mwanza, Tanzania.
Malik FakharDepartment of Neurology, Weill Cornell Medicine, New York, New York, USA.
Philip E StiegWeill Cornell Brain and Spine Center, Department of Neurological Surgery, Weill Cornell Medicine, New York, New York, USA.
Roger HärtlWeill Cornell Brain and Spine Center, Department of Neurological Surgery, Weill Cornell Medicine, New York, New York, USA.
Cornell University · USBugando Medical Centre · TZ

Funding

Clinical and Translational Science CenterUL1TR000457 · NCATS · WEILL MEDICAL COLL OF CORNELL UNIV · PI IMPERATO-MCGINLEY, JULIANNE L · 2012 to 2016
$46.0M
Vanderbilt-Emory-Cornell-Duke Global Health Fellowship Consortium-Expanding Diversity for Global Equity (EDGE)D43TW009337 · FIC · VANDERBILT UNIVERSITY MEDICAL CENTER · PI ALIYU, MUKTAR HASSAN, HEIMBURGER, DOUGLAS CORBETT · 2017 to 2021
$6.3M
Vanderbilt-Emory-Cornell-Duke Consortium for Global Health Fellows (VECDor)R25TW009337 · FIC · VANDERBILT UNIVERSITY MEDICAL CENTER · PI HEIMBURGER, DOUGLAS CORBETT, VERMUND, STEN H. · 2012 to 2016
$6.3M
Hypertension in HIV-Infected Tanzanians: Time Course and PathogenesisK01TW010281 · FIC · WEILL MEDICAL COLL OF CORNELL UNIV · PI PECK, ROBERT N · 2015 to 2019
$689k
FIC NIH HHS D43 TW009337FIC NIH HHS K01 TW010281FIC NIH HHS R25 TW009337NCATS NIH HHS UL1 TR000457
6 · The paper itself

Abstract

backgroundSevere traumatic brain injury (TBI) is a major cause of death and disability worldwide. Prospective TBI data from sub-Saharan Africa are sparse. This study examines epidemiology and explores management of patients with severe TBI and adherence to Brain Trauma Foundation Guidelines at a tertiary care referral hospital in Tanzania.

methodsPatients with severe TBI hospitalized at Bugando Medical Centre were recorded in a prospective registry including epidemiologic, clinical, treatment, and outcome data.

resultsBetween September 2013 and October 2015, 371 patients with TBI were admitted; 33% (115/371) had severe TBI. Mean age was 32.0 years ± 20.1, and most patients were male (80.0%). Vehicular injuries were the most common cause of injury (65.2%). Approximately half of the patients (47.8%) were hospitalized on the day of injury. Computed tomography of the brain was performed in 49.6% of patients, and 58.3% were admitted to the intensive care unit. Continuous arterial blood pressure monitoring and intracranial pressure monitoring were not performed in any patient. Of patients with severe TBI, 38.3% received hyperosmolar therapy, and 35.7% underwent craniotomy. The 2-week mortality was 34.8%.

conclusionsMortality of patients with severe TBI at Bugando Medical Centre, Tanzania, is approximately twice that in high-income countries. Intensive care unit care, computed tomography imaging, and continuous arterial blood pressure and intracranial pressure monitoring are underused or unavailable in the tertiary referral hospital setting. Improving outcomes after severe TBI will require concerted investment in prehospital care and improvement in availability of intensive care unit resources, computed tomography, and expertise in multidisciplinary care.

Indexed as

AdolescentAdultBrain Injuries, TraumaticFemaleGlasgow Coma ScaleGuideline AdherenceHumansMaleMiddle AgedRetrospective StudiesTanzaniaTertiary Care CentersYoung AdultAdherenceGuidelinesMortalitySub-Saharan AfricaTanzaniaTraumatic brain injury

Identifiers

PMID28559070
PMCPMC5575962
OpenAlexW2619394762

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.