ArticleParasites & vectors2017
Genetic variation of mitochondrial genes among Echinococcus multilocularis isolates collected in western China.
Article in Parasites & vectors, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
17 citing papers in PubMed, 27 citations in OpenAlex.
- Equine alveolar echinococcosis: a focus on epidemiology, clinical and pathological features, and diagnostics.Journal of equine science · 2026Review
- Molecular identification and genetic diversity of Echinococcus granulosus sensu stricto in livestock from Qinghai lake on the Qinghai-Tibetan plateau.Veterinary research communications · 2026Article
- The genetic variation of mitochondrial sequences and pathological differences ofMicrobiology spectrum · 2025Article
- A Case Series and Literature Review of Alveolar Echinococcosis in Kashmir, India: An Emerging Endemic Zone forLife (Basel, Switzerland) · 2024Article
- Molecular phylogenetic analysis ofFood and waterborne parasitology · 2024Article
- Investigation and genetic polymorphism analysis of rodents infected withFrontiers in cellular and infection microbiology · 2024Article
- Canine Alveolar Echinococcosis: An Emerging and Costly Introduced Problem in North America.Transboundary and emerging diseases · 2023Article
- Genetic characterization of human echinococcosis in Southern Punjab, Pakistan.Frontiers in cellular and infection microbiology · 2023Article
- Genetic diversity ofVeterinary world · 2022Article
- Occurrence and genetic characterization of Echinococcus granulosus sensu lato from domestic animals in Central Iran.BMC veterinary research · 2022Article
- Article
- High endemicity of alveolar echinococcosis in Yili Prefecture, Xinjiang Autonomous Region, the People's Republic of China: Infection status in different ethnic communities and in small mammals.PLoS neglected tropical diseases · 2021Article
- The Molecular Epidemiology ofPathogens (Basel, Switzerland) · 2020Review
- Genetic diversity of Echinococcus multilocularis and Echinococcus granulosus sensu lato in Kyrgyzstan: The A2 haplotype of E. multilocularis is the predominant variant infecting humans.PLoS neglected tropical diseases · 2020Article
- Echinococcosis: Advances in the 21st Century.Clinical microbiology reviews · 2019Review
- Knowledge Domain and Emerging Trends on Echinococcosis Research: A Scientometric Analysis.International journal of environmental research and public health · 2019Article
- Sequence analysis of mitochondrial cytochrome c oxidase 1 and cytochrome b genes of echinococcus multilocularis from human patients.International journal of clinical and experimental pathology · 2018Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
14 authors at 4 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundAlveolar echinococcosis (AE) is a life-threatening human disease caused by Echinococcus multilocularis transmitted between rodents and dogs/foxes in the Northern Hemisphere. The study aims to identify the genetic variation of the parasite in AE patients from China.
methodsE. multilocularis isolates were collected from wild small mammals (n = 6) and AE patients (n = 56) from western China. Genomic DNA was extracted from different tissue samples including paraffin tissue blocks, ethanol fixed tissues and frozen tissues surgically removed. Two mitochondrial gene fragments (526 bp for cob and 474 bp for nad2) of E. multilocularis were amplified and sequenced.
resultsThe parasite fragment sequences of cob fragments from AE patients showed two haplotypes, and nad2 gene fragment sequences had four haplotypes. The gene sequences from Microtus sp. were 100% identical to the sequences of some isolates from AE patients. These haplotypes were distributed in both Qinghai and Xinjiang provinces. Alignment analysis with the sequences from the GenBank databases showed five genotypes including three Asian genotypes, one from Europe and one from North America.
conclusionsMost AE patients harbored the Asian genotype 1 which may be an indication of its relative frequency in the definitive hosts and the environment or of its pathogenicity to humans, which calls for further research.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.