ArticleBMC veterinary research2017
Comparison of the fecal bacterial microbiota of healthy and diarrheic foals at two and four weeks of life.
Article in BMC veterinary research, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
34 citing papers in PubMed.
- Early Gut Microbiota and Metabolic Profiles of Neonatal Donkey Foals and a Comparative Study with Maternal Communities.Microorganisms · 2026Article
- A Comprehensive Review of the Equine Gut Microbiome in Health and Disease.Veterinary sciences · 2026Review
- Starch Overload and Cecal Alkalinization: Impacts on the Intestinal Microbiota and Health of Horses.Veterinary and animal science · 2026Article
- Survey on Faecal Microbiota Transplantation and Probiotic Use in Equine Practice in France and Belgium.Veterinary medicine and science · 2026Article
- An Overview of Donkey Neonatology.Animals : an open access journal from MDPI · 2025Review
- Dietary supplementation of new-born foals with free nucleotides positively affects neonatal diarrhoea management.Irish veterinary journal · 2025Article
- Use of biotics in animals: impact on nutrition, health, and food production.Journal of animal science · 2025Review
- Gut microbiome regulation in equine animals: current understanding and future perspectives.Frontiers in microbiology · 2025Review
- Relationship between the components of mare breast milk and foal gut microbiome: shaping gut microbiome development after birth.The veterinary quarterly · 2024Article
- Dysbiosis not observed in Canadian horse with free fecal liquid (FFL) using 16S rRNA sequencing.Scientific reports · 2024Article
- Supplementation of Foals with aAnimals : an open access journal from MDPI · 2024Article
- Comparing microbiotas of foals and their mares' milk in the first two weeks after birth.BMC veterinary research · 2024Article
- Expanded catalogue of metagenome-assembled genomes reveals resistome characteristics and athletic performance-associated microbes in horse.Microbiome · 2023Article
- Conserved core microbiota in managed and free-rangingFrontiers in microbiology · 2023Article
- Effects of different grains on bacterial diversity and enzyme activity associated with digestion of starch in the foal stomach.BMC veterinary research · 2022Article
- Effects of Short-Chain Fatty Acid Modulation on Potentially Diarrhea-Causing Pathogens in Yaks Through Metagenomic Sequencing.Frontiers in cellular and infection microbiology · 2022Article
- Article
- Gut Microbiota Manipulation in Foals-Naturopathic Diarrhea Management, or Unsubstantiated Folly?Pathogens (Basel, Switzerland) · 2021Review
- Transport stress affects the fecal microbiota in healthy donkeys.Journal of veterinary internal medicine · 2021Article
- Changes in the Fecal Microbiota Associated with a Broad-Spectrum Antimicrobial Administration in Hospitalized Neonatal Foals with Probiotics Supplementation.Animals : an open access journal from MDPI · 2021Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundDiarrhea in foals affects up to 60% of foals during the first six months of life. The effect of diarrhea on the fecal bacterial microbiota in foals has not been investigated. Little is known on the fecal bacterial microbial richness and diversity of foals at a young age. The objective was to compare the fecal bacterial microbiota of healthy foals to foals with diarrhea at two and four weeks of life.
methodsFecal samples were collected from foals (n = 20) at 1-14 (T1) and 15-28 (T2) days of age and analyzed using high throughput sequencing. Differences in relative abundance of bacterial taxa, alpha diversity and beta diversity indices were assessed between age-matched foals with diarrhea (n = 9) and healthy foals (n = 11), and between time points.
resultsDifferences in microbial community composition based on time point and health status were observed on all taxonomic levels. Of 117 enriched species in healthy foals at T2, 50 (48%) were Lachnospiraceae or Ruminococcaceae. The Chao richness index was increased in healthy foals at T2 compared to T1 (p = 0.02). Foals with diarrhea had a significantly lower richness index than non-diarrheic foals at T2 (p = 0.04). Diarrhea had an inconsistent effect, while time point had a consistent effect on microbial community structure.
conclusionsPreventative and therapeutic measures for diarrhea should focus on maintaining bacterial microbiota richness. Lachnospiraceae and Ruminococcaceae were underrepresented in foals with diarrhea. These should be evaluated further as potential therapeutic options.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.