ArticleBMC plant biology2017
Global identification, structural analysis and expression characterization of bHLH transcription factors in wheat.
Article in BMC plant biology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 41 papers.
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41 citing papers in PubMed, 77 citations in OpenAlex.
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- Genome-Wide Identification and Analysis of bHLH Transcription Factors Related to Anthocyanin Biosynthesis inInternational journal of molecular sciences · 2023Article
- Genome-wide identification, expression analysis, and potential roles under low-temperature stress of bHLH gene family inFrontiers in plant science · 2023Article
- Genome-wide identification and characterization of bHLH family genes from orchardgrass and the functional characterization of DgbHLH46 and DgbHLH128 in drought and salt tolerance.Functional & integrative genomics · 2022Article
- Genome-wide identification and characterization of AP2/ERF gene superfamily during flower development in Actinidia eriantha.BMC genomics · 2022Article
- The PGS1 basic helix-loop-helix protein regulates Fl3 to impact seed growth and grain yield in cereals.Plant biotechnology journal · 2022Article
- Regulation of Phenolic Compound Production by Light Varying in Spectral Quality and Total Irradiance.International journal of molecular sciences · 2022Article
Corrections and comments
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Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundBasic helix-loop-helix (bHLH) transcription factors (TFs), which are widely distributed in eukaryotic organisms, play crucial roles in plant development. However, no comprehensive analysis of the bHLH family in wheat (Triticum aestivum L.) has been undertaken previously.
resultsIn this study, 225 bHLH TFs predicted from wheat using genomic and RNA sequencing data were subjected to identification, classification, phylogenetic reconstruction, conserved motif characterization, chromosomal distribution determination and expression pattern analysis. One basic region, two helix regions and one loop region were found to be conserved in wheat bHLH TFs. The bHLH proteins could be separated into four categories based on sequences in their basic regions. Neighbor-joining-based phylogenetic analysis of conserved bHLH domains from wheat, Arabidopsis and rice identified 26 subfamilies of bHLH TFs, of which 23 were found in wheat. A total of 82 wheat bHLH genes had orthologs in Arabidopsis (27 TFs), rice (28 TFs) and both of them (27 TFs). Seven tissue-specific bHLH TF clusters were identified according to their expression patterns in endosperm, aleurone, seedlings, heading-stage spikes, flag leaves, shoots and roots. Expression levels of six endosperm-specifically expressed TFs measured by qPCR and RNA-seq showed a good correlation.
conclusionThe 225 bHLH transcription factors identified from wheat could be classed into 23 subfamilies, and those members from the same subfamily with similar sequence motifs generally have similar expression patterns.
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