ArticleBMC endocrine disorders2017
Association of calf circumference with insulin resistance and non-alcohol fatty liver disease: the REACTION study.
Article in BMC endocrine disorders, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
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Who cites it
7 citing papers in PubMed.
- The association of calf circumference with nutritional risk and mortality in type 2 diabetes aged over 80 years inpatient Chinese.Diabetology & metabolic syndrome · 2025Article
- Relatively lower BMI-adjusted calf circumference is associated with metabolically unhealthy phenotype in non-obese adults: a cross-sectional study.BMC public health · 2024Article
- Regional fat distribution and hepatic fibrosis and steatosis severity in patients with nonalcoholic fatty liver disease and type 2 diabetes.Obesity science & practice · 2024Article
- Association between Height-Changing Scores and Risk of Sarcopenia Estimated from Anthropometric Measurements in Older Adults: A Cross-Sectional Study.Healthcare (Basel, Switzerland) · 2024Article
- Semiparametric modeling for the cardiometabolic risk index and individual risk factors in the older adult population: A novel proposal.PloS one · 2024Article
- The Correlation Between Leg Muscle Mass Index and Non-Alcoholic Fatty Liver Disease in Patients with Type 2 Diabetes Mellitus.Diabetes, metabolic syndrome and obesity : targets and therapy · 2023Article
- Calf circumference predicts frailty in older adults: the Chinese longitudinal healthy longevity survey.BMC geriatrics · 2022Article
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Authors and funding
11 authors.
Funding
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Abstract
backgroundThe feature of nonalcoholic fatty liver disease (NAFLD) is pathological excessive liver lipid accumulation of subjects who without history of alcohol abuse. Calf circumference is a proxy for lower-body fat and screening method for the identification of subjects with acatastatic lipid accumulation. The objective of this study was to examine the association between calf circumference and NAFLD.
methodsThe study was a cross-sectional analysis including 8850 middle-aged and elderly individuals. NAFLD was examined by hepatic ultrasound and without alcohol abuse and other liver diseases. Calf circumference was measured on the lower right leg at the point of maximal circumference.
resultsThe mean of calf circumference were 35.7 cm for male and 34.6 cm for female (P < 0.001), respectively. Compared with the lowest calf circumference quartile, the odds ratio for NAFLD in the highest quartile was 2.73 (95% CI 2.34-3.19, P
conclusionHigh calf circumference is significantly associated with elevated prevalence of NAFLD and increasing insulin resistance.
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