Evidence map›Paper›PMID 28558129›Full record

ArticleHippocampus2017

Somatostatin depresses the excitability of subicular bursting cells: Roles of inward rectifier K

Binqi Hu, Nicholas I Cilz, Saobo Lei

Open access · greenAbstract read
In one paragraph

Article in Hippocampus, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
0.8field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 22 citations in OpenAlex.

  1. Article
  2. Neuropeptidergic systems in psychiatric disorders.Frontiers in endocrinology · 2025
    Review
  3. Article
  4. Article
  5. Cell-Type-Specific Effects of Somatostatin on Synaptic Transmission in the Anterior Cingulate Cortex.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2024
    Article
  6. Article
  7. Review
  8. Article
  9. Evidence for Dual Activation ofInternational journal of molecular sciences · 2022
    Article
  10. Roles of PLCβ, PIPJournal of cellular physiology · 2022
    Article
  11. Article
  12. Development, Diversity, and Death of MGE-Derived Cortical Interneurons.International journal of molecular sciences · 2021
    Review
  13. Activation of VNeuropharmacology · 2021
    Article
  14. Article
  15. Article
  16. Review
  17. Article
  18. Roles of KNeuropharmacology · 2019
    Article
  19. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Binqi HuDepartment of Biomedical Sciences, School of Medicine and Health Sciences, University of North Dakota, Grand Forks, North Dakota 58203.
Nicholas I CilzDepartment of Biomedical Sciences, School of Medicine and Health Sciences, University of North Dakota, Grand Forks, North Dakota 58203.ORCID 0000-0002-9012-6517
Saobo LeiDepartment of Biomedical Sciences, School of Medicine and Health Sciences, University of North Dakota, Grand Forks, North Dakota 58203.
University of North Dakota · US

Funding

Roles and mechanisms of neurotensin in learning and memoryR01MH082881 · NIMH · UNIVERSITY OF NORTH DAKOTA · PI LEI, SAOBO · 2008 to 2015
$2.5M
NIMH NIH HHS R01 MH082881
6 · The paper itself

Abstract

The hippocampus is a crucial component for cognitive and emotional processing. The subiculum provides much of the output for this structure but the modulation and function of this region is surprisingly under-studied. The neuromodulator somatostatin (SST) interacts with five subtypes of SST receptors (sst

Indexed as

Action PotentialsAnimalsAnimals, NewbornCalciumCyclic AMPEnzyme InhibitorsGuanine Nucleotide Exchange FactorsHippocampusKCNQ Potassium ChannelsLong-Term PotentiationModels, BiologicalNerve NetNeuronsNeurotransmitter AgentsPotassium Channel BlockersRatsCalciumCyclic AMPEnzyme InhibitorsGuanine Nucleotide Exchange FactorsKCNQ Potassium ChannelsNeurotransmitter AgentsPotassium Channel BlockersRapgef3 protein, ratSodium Channel BlockersSomatostatinTetrodotoxinglutamateneuromodulationpeptidesubiculumsynaptic transmission

Identifiers

PMID28558129
PMCPMC5793910
OpenAlexW2620419141

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.