ArticlePloS one2017
The disease burden of congenital toxoplasmosis in Denmark, 2014.
Article in PloS one, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 2 of them syntheses that pooled it.
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Who cites it
12 citing papers in PubMed, 2 syntheses or guidelines pooled it, 27 citations in OpenAlex.
- Relationship between Toxoplasma gondii infection and psychiatric disorders in Iran: A systematic review with meta-analysis.PloS one · 2023Pooled it
- Toxoplasmosis infection among pregnant women in Africa: A systematic review and meta-analysis.PloS one · 2021Pooled it
- Evaluating Toxoplasmosis Molecular Prevalence in Slaughtered Sheep using PCR Assay in Northern Palestine.Acta parasitologica · 2026Article
- The disease burden of ocular toxoplasmosis in Denmark in 2019: Estimates based on laboratory testing of ocular samples and on publicly available register data.Parasite epidemiology and control · 2021Article
- Prevalence and risk factors for exposure to Toxoplasma gondii in slaughterhouse workers in western Kenya.BMC infectious diseases · 2021Article
- Burden of foodborne diseases: think global, act local.Current opinion in food science · 2021Review
- Morphological and biochemical repercussions ofBrain, behavior, & immunity - health · 2021Article
- Seroprevalence ofParasite epidemiology and control · 2019Review
- Toxoplasma gondii seroprevalence in extensively farmed wild boars (Sus scrofa) in Denmark.Acta veterinaria Scandinavica · 2019Article
- Direct genetic characterization of Toxoplasma gondii from clinical samples from Denmark: not only genotypes II and III.European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2018Article
- Congenital Toxoplasmosis: A Plea for a Neglected Disease.Pathogens (Basel, Switzerland) · 2018Article
- Risk ranking of foodborne parasites: State of the art.Food and waterborne parasitologyReview
Corrections and comments
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Authors and funding
8 authors at 5 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundCongenital toxoplasmosis (CT) causes a substantial disease burden worldwide. The aim of this study was to estimate the disease burden of CT in Denmark, a developed country with free public healthcare and nationwide data available.
methodsUsing data primarily from two public health surveillance programmes conducted between 1992 and 2007, we estimated the incidence, occurrence of sequelae, mortality and the burden of disease in terms of disability-adjusted life years (DALYs) of CT in Denmark in 2014.
findingsWe estimated that 14 children were born with CT in 2014, of which six will have developed sequelae by the age of 12. CT resulted in a total disease burden of 123 DALYs (95% uncertainty interval [UI], 100-148), of which 78 (95% UI, 64-94) were due to foetal loss and 2 (95% UI, 1-3) were due to neonatal death; the remaining burden was due to moderate to severe life-long sequelae. A comparison of the estimated incidence of CT with the number of reported CT cases in 2008-2014 indicated that for each reported CT case, at least five other CT cases could be expected to have occurred and gone unreported.
interpretationEarly onset, severity, and life-long duration of sequelae have a major effect on the disease burden of CT. Our data suggest that CT is under-diagnosed or under-reported in Denmark. The estimated disease burden and public health impact in Denmark is lower than in other European countries, highlighting the need for country-specific studies.
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