ArticlePloS one2017
Yellow-Leaf 1 encodes a magnesium-protoporphyrin IX monomethyl ester cyclase, involved in chlorophyll biosynthesis in rice (Oryza sativa L.).
Article in PloS one, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
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13 citing papers in PubMed, 38 citations in OpenAlex.
- Integrative Multi-Omics Analysis Reveals Systemic Transcriptional and Hormonal Reprogramming Associated with a Rice Yellow-Green Leaf Mutant.Current issues in molecular biology · 2026Article
- Deletion of the gene encoding the magnesium chelatase I subunit resulted in a novel wheat leaf colour mutant.Plant biotechnology journal · 2025Article
- Comprehensive Identification of Key Genes Responsible for Leaf Senescence of Rice (Plants (Basel, Switzerland) · 2025Article
- Review
- Fine Mapping and Screening of Candidate Gene for Yellow-to-Green Mutation in Snap Bean (International journal of molecular sciences · 2025Article
- Map-based cloning and characterization ofMolecular breeding : new strategies in plant improvement · 2024Article
- Genome-wide identification of theFrontiers in plant science · 2022Article
- Genome-Wide Investigation of theFrontiers in plant science · 2022Article
- Mutation in Mg-Protoporphyrin IX Monomethyl Ester (Oxidative) Cyclase GeneFrontiers in plant science · 2022Article
- iTRAQ-based comparative proteomic analysis of differences in the protein profiles of stems and leaves from two alfalfa genotypes.BMC plant biology · 2020Article
- Identification of two recessive etiolation genes (py1, py2) in pakchoi (Brassica rapa L. ssp. chinensis).BMC plant biology · 2020Article
- Combining a New Exome Capture Panel With an Effective varBScore Algorithm Accelerates BSA-Based Gene Cloning in Wheat.Frontiers in plant science · 2020Article
- Impaired Magnesium Protoporphyrin IX Methyltransferase (ChlM) Impedes Chlorophyll Synthesis and Plant Growth in Rice.Frontiers in plant science · 2017Article
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11 authors at 3 institutions in 1 country.
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Abstract
Magnesium-protoporphyrin IX monomethyl ester cyclase (MPEC) catalyzes the conversion of MPME to divinyl protochlorophyllide (DVpchlide). This is an essential enzyme during chlorophyll (Chl) biosynthesis but details of its function in rice are still lacking. Here, we identified a novel rice mutant yellow-leaf 1 (yl-1), which showed decreased Chl accumulation, abnormal chloroplast ultrastructure and attenuated photosynthetic activity. Map-based cloning and over-expression analysis suggested that YL-1 encodes a subunit of MPEC. The YL-1 protein localizes in chloroplasts, and it is mainly expressed in green tissues, with greatest abundance in leaves and young panicles. Results of qRT-PCR showed that Chl biosynthesis upstream genes were highly expressed in the yl-1 mutant, while downstream genes were compromised, indicating that YL-1 plays a pivotal role in the Chl biosynthesis. Furthermore, the expression levels of photosynthesis and chloroplast development genes were also affected. RNA-seq results futher proved that numerous membrane-associated genes, including many plastid membrane-associated genes, have altered expression pattern in the yl-1 mutant, implying that YL-1 is required for plastid membrane stability. Thus, our study confirms a putative MPME cyclase as a novel key enzyme essential for Chl biosynthesis and chloroplast membrane stability in rice.
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