ArticlePloS one2017
Treatment of AKI in developing and developed countries: An international survey of pediatric dialysis modalities.
Article in PloS one, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
25 citing papers in PubMed, 61 citations in OpenAlex.
- Gravity-assisted continuous flow peritoneal dialysis technique use in acute kidney injury in children: a randomized, crossover clinical trial.Pediatric nephrology (Berlin, Germany) · 2023Trial
- Outcomes of pediatric urgent-start peritoneal dialysis: a single-center experience from Jordan.Renal failure · 2026Article
- Sustained low-efficiency dialysis-an old method but possibly a new solution for environmental nephrology.Renal failure · 2025Review
- Enhancing outcomes in pediatric populations with continuous renal replacement therapy: Current multidisciplinary strategies and innovations.Journal of intensive medicine · 2025Review
- Innovation of a Neonatal Peritoneal Dialysis Catheter to Expand Dialysis Capabilities for Critically Ill Neonates in Low-Resource Settings.Blood purification · 2025Article
- A Detailed Description of Locally Available Peritoneal Dialysis in a Low-Resource Setting: A Case Report.Case reports in nephrology · 2025Article
- Dialysis for paediatric acute kidney injury in Cape Town, South Africa.Pediatric nephrology (Berlin, Germany) · 2024Article
- Structures, Organization, and Delivery of Kidney Care to Children Living in Low-Resource Settings.Kidney international reports · 2024Article
- Is SLED Efficient in Sepsis Associated Acute Kidney Injury: Hope but Hold!!Indian journal of critical care medicine : peer-reviewed, official publication of Indian Society of Critical Care Medicine · 2024Article
- New perspectives in pediatric dialysis technologies: the case for neonates and infants with acute kidney injury.Pediatric nephrology (Berlin, Germany) · 2024Article
- Epidemiology data on the cost and outcomes associated with pediatric acute kidney injury.Pediatric research · 2023Article
- Archetypal sustained low-efficiency daily diafiltration (SLEDD-f) for critically ill patients requiring kidney replacement therapy: towards an adequate therapy.Journal of nephrology · 2023Review
- Paediatric nephrology in under-resourced areas.Pediatric nephrology (Berlin, Germany) · 2022Review
- Neonatal acute kidney injury risk stratification score: STARZ study.Pediatric research · 2022Article
- Perspectives: Neonatal acute kidney injury (AKI) in low and middle income countries (LMIC).Frontiers in pediatrics · 2022Article
- Advances in pediatric acute kidney injury.Pediatric research · 2022Review
- Pediatric acute kidney injury: new advances in the last decade.Kidney research and clinical practice · 2021Article
- Challenges of access to kidney care for children in low-resource settings.Nature reviews. Nephrology · 2021Review
- Renal Replacement Therapy in Pediatric Acute Kidney Injury.Indian journal of pediatrics · 2020Review
- Dialysis modalities for the management of pediatric acute kidney injury.Pediatric nephrology (Berlin, Germany) · 2020Review
Corrections and comments
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Authors and funding
8 authors at 7 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
hypothesisAcute kidney injury (AKI) is a common cause of morbidity and mortality worldwide, with a pediatric incidence ranging from 19.3% to 24.1%. Treatment of pediatric AKI is a source of debate in varying geographical regions. Currently CRRT is the treatment for pediatric AKI, but limitations due to cost and accessibility force use of adult equipment and other therapeutic options such as peritoneal dialysis (PD) and hemodialysis (HD). It was hypothesized that more cost-effective measures would likely be used in developing countries due to lesser resource availability.
methodsA 26-question internet-based survey was distributed to 650 pediatric Nephrologists. There was a response rate of 34.3% (223 responses). The survey was distributed via pedneph and pcrrt email servers, inquiring about demographics, technology, resources, pediatric-specific supplies, and preference in renal replacement therapy (RRT) in pediatric AKI. The main method of analysis was to compare responses about treatments between nephrologists in developed countries and nephrologists in developing countries using difference-of-proportions tests.
resultsPD was available in all centers surveyed, while HD was available in 85.1% and 54.1% (p = 0.00), CRRT was available in 60% and 33.3% (p = 0.001), and SLED was available in 20% and 25% (p = 0.45) centers of developed and developing world respectively. In developing countries, 68.5% (p = 0.000) of physicians preferred PD to costlier therapies, while in developed countries it was found that physicians favored HD (72%, p = 0.00) or CRRT (24%, p = 0.041) in infants.
conclusionsLack of availability of resources, trained physicians and funds often preclude standards of care in developing countries, and there is much development needed in terms of meeting higher global standards for treating pediatric AKI patients. PD remains the main modality of choice for treatment of AKI in infants in developing world.
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