ArticlePLoS computational biology2017
Adaptation towards scale-free dynamics improves cortical stimulus discrimination at the cost of reduced detection.
Article in PLoS computational biology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 35 papers, 1 of them a synthesis that pooled it.
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Who cites it
35 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Is criticality a unified setpoint of brain function?Neuron · 2025Pooled it
- Diminished Signal-to-Noise Ratio Disrupts Somatosensory Population Encoding and Drives Tactile Hyposensitivity in the Fmr1Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026Article
- Power Laws in Empirical Eigenvalue Spectra.Entropy (Basel, Switzerland) · 2026Article
- Emergent critical oscillations in motor cortex of Parkinson's patients.bioRxiv : the preprint server for biology · 2026Article
- Harnessing Intelligence from Brain Cells In Vitro.The Neuroscientist : a review journal bringing neurobiology, neurology and psychiatry · 2025Review
- Genetic contributions to brain criticality and its relationship with human cognitive functions.Proceedings of the National Academy of Sciences of the United States of America · 2025Article
- Evolutionary Implications of Self-Assembling Cybernetic Materials with Collective Problem-Solving Intelligence at Multiple Scales.Entropy (Basel, Switzerland) · 2024Article
- Low-dimensional criticality embedded in high-dimensional awake brain dynamics.Science advances · 2024Article
- Trial-by-trial variability in cortical responses exhibits scaling of spatial correlations predicted from critical dynamics.Cell reports · 2024Article
- The technology, opportunities, and challenges of Synthetic Biological Intelligence.Biotechnology advances · 2023Review
- Critical dynamics arise during structured information presentation within embodied in vitro neuronal networks.Nature communications · 2023Article
- Synchronization and oscillation behaviors of excitatory and inhibitory populations with spike-timing-dependent plasticity.Cognitive neurodynamics · 2023Article
- Mechanisms of human dynamic object recognition revealed by sequential deep neural networks.PLoS computational biology · 2023Article
- Article
- Sampling effects and measurement overlap can bias the inference of neuronal avalanches.PLoS computational biology · 2022Article
- Replay, the default mode network and the cascaded memory systems model.Nature reviews. Neuroscience · 2022Review
- Criticality enhances the multilevel reliability of stimulus responses in cortical neural networks.PLoS computational biology · 2022Article
- Stable representation of a naturalistic movie emerges from episodic activity with gain variability.Nature communications · 2021Article
- Neuronal Avalanches Across the Rat Somatosensory Barrel Cortex and the Effect of Single Whisker Stimulation.Frontiers in systems neuroscience · 2021Article
- Stability of motor cortex network states during learning-associated neural reorganizations.Journal of neurophysiology · 2020Article
Corrections and comments
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4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Fundamental to the function of nervous systems is the ability to reorganize to cope with changing sensory input. Although well-studied in single neurons, how such adaptive versatility manifests in the collective population dynamics and function of cerebral cortex remains unknown. Here we measured population neural activity with microelectrode arrays in turtle visual cortex while visually stimulating the retina. First, we found that, following the onset of stimulation, adaptation tunes the collective population dynamics towards a special regime with scale-free spatiotemporal activity, after an initial large-scale transient response. Concurrently, we observed an adaptive tradeoff between two important aspects of population coding-sensory detection and discrimination. As adaptation tuned the cortex toward scale-free dynamics, stimulus discrimination was enhanced, while stimulus detection was reduced. Finally, we used a network-level computational model to show that short-term synaptic depression was sufficient to mechanistically explain our experimental results. In the model, scale-free dynamics emerge only when the model operates near a special regime called criticality. Together our model and experimental results suggest unanticipated functional benefits and costs of adaptation near criticality in visual cortex.
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