ReviewCurrent opinion in obstetrics & gynecology2017
Female exposure to endocrine disrupting chemicals and fecundity: a review.
Review in Current opinion in obstetrics & gynecology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03733912 (To Investigate the Effect of Plasticizers on the Pregnancy in Vitro Fertilization Cycles), which is not on this map. Cited by 25 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
To Investigate the Effect of Plasticizers on the Pregnancy in Vitro Fertilization Cycles
Who cites it
25 citing papers in PubMed, 69 citations in OpenAlex.
- The silent crisis: investigating the impact of environmental pollutants on embryo-fetal development: a narrative review of the Group of Special Interest for Environment of the Italian Society of Fertility and Sterility and Reproductive Medicine.Journal of assisted reproduction and genetics · 2025Review
- Phenol biomarker concentrations in human ovarian follicular fluid and the associations with in-vitro fertilization outcomes.International journal of hygiene and environmental health · 2025Article
- Prenatal exposure to an environmentally relevant phthalate mixture alters serum cytokine levels and inflammatory markers in the F1 mouse ovary.Toxicological sciences : an official journal of the Society of Toxicology · 2024Article
- Evaluating associations of bisphenol and phthalate exposure with time to pregnancy and subfecundity in a New York City pregnancy cohort.Environmental pollution (Barking, Essex : 1987) · 2024Article
- Endocrine-disrupting chemicals and male reproductive health.Fertility and sterility · 2023Review
- Perceived stress and markers of ovarian reserve among subfertile women.Reproductive biomedicine online · 2023Observational
- Association of triclosan and human infertility: A systematic review.Environmental analysis, health and toxicology · 2023Article
- Urinary phenol concentrations and fecundability and early pregnancy loss.Human reproduction (Oxford, England) · 2023Article
- Association between chemical mixtures and female fertility in women undergoing assisted reproduction in Sweden and Estonia.Environmental research · 2023Article
- Bitter Taste Receptors and Endocrine Disruptors: Cellular and Molecular Insights from an In Vitro Model of Human Granulosa Cells.International journal of molecular sciences · 2022Article
- Untargeted metabolomics reveals that multiple reproductive toxicants are present at the endometrium.The Science of the total environment · 2022Article
- Environmental factors in declining human fertility.Nature reviews. Endocrinology · 2022Review
- Impact of Triclosan on Female and Male Reproductive System and Its Consequences on Fertility: A Literature Review.Journal of family & reproductive health · 2022Review
- Evaluation of Triclosan Effects on Cultured Swine Luteal Cells.Animals : an open access journal from MDPI · 2021Article
- Effects of Environmental EDCs on Oocyte Quality, Embryo Development, and the Outcome in Human IVF Process.Advances in experimental medicine and biology · 2021Article
- Simultaneous determination of 11 antiseptic ingredients in surface water based on polypyrrole decorated magnetic nanoparticles.RSC advances · 2020Article
- Environmental risk factors for endometriosis: A critical evaluation of studies and recommendations from the epidemiologic perspective.Current epidemiology reports · 2020Article
- Human exposure to synthetic endocrine disrupting chemicals (S-EDCs) is generally negligible as compared to natural compounds with higher or comparable endocrine activity: how to evaluate the risk of the S-EDCs?Archives of toxicology · 2020Article
- Association Between the Frequency of Eating Non-home-prepared Meals and Women Infertility in the United States.Journal of preventive medicine and public health = Yebang Uihakhoe chi · 2020Article
- Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 1 institution in 1 country.
Funding
Abstract
purpose of reviewEndocrine disrupting chemicals (EDCs) have been known for their ability to interfere with aspects of hormone action resulting in adverse health consequences among animals and humans; however, the effects of EDCs on human fecundity have shown inconsistent findings. This review summarizes the most recent epidemiologic literature from humans on the potential effects of female exposure to nonpersistent EDCs, specifically bisphenol A (BPA), phthalates, parabens, and triclosan, on fecundity, measured by markers of reproductive hormones, markers of ovulation or ovarian reserve, IVF outcomes, and time-to-pregnancy. RECENT
findingsAlthough the epidemiologic literature on this topic is growing, the evidence supporting an association between female urinary concentrations of BPA, phthalates, parabens and triclosan, and fecundity remains unclear. The heterogeneous results could be due to methodological differences in recruitment populations (fertile vs. subfertile), study designs (prospective vs. retrospective), assessment of exposure (including differences in the number and timing of urine samples and differences in the analytical methods used to assess the urinary concentrations), residual confounding due to diet or other lifestyle factors, and coexposures to other chemicals. SUMMARY: At present, there is limited evidence to conclude that female exposure to nonpersistent EDCs affect fecundity in humans. Further studies focusing on exposure to mixtures of EDCs are needed.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.