Evidence map›Paper›PMID 28557711›Full record

ArticleEnvironmental health perspectives2017

Prenatal Residential Proximity to Agricultural Pesticide Use and IQ in 7-Year-Old Children.

Robert B Gunier, Asa Bradman, Kim G Harley, Katherine Kogut, Brenda Eskenazi

Abstract read
In one paragraph

Article in Environmental health perspectives, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 97 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
97citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

97 citing papers in PubMed, 2 syntheses or guidelines pooled it.

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  16. Personal air sampling for pesticides in the California San Joaquin Valley.Journal of exposure science & environmental epidemiology · 2025
    Article
  17. Sociability: Comparing the Effect of Chlorpyrifos with Valproic Acid.Journal of autism and developmental disorders · 2025
    Article
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37 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Robert B GunierSchool of Public Health, University of California, Berkeley, Berkeley, California, USA.
Asa BradmanSchool of Public Health, University of California, Berkeley, Berkeley, California, USA.
Kim G HarleySchool of Public Health, University of California, Berkeley, Berkeley, California, USA.
Katherine KogutSchool of Public Health, University of California, Berkeley, Berkeley, California, USA.
Brenda EskenaziSchool of Public Health, University of California, Berkeley, Berkeley, California, USA.

Funding

Project C: Epigenetic Effects of DDT/E and PBDEs on PubertyP01ES009605 · NIEHS · UNIVERSITY OF CALIFORNIA BERKELEY · PI ESKENAZI, BRENDA · 1999 to 2015
$11.2M
Current-use fumigants: Health effects of prenatal and early childhood exposuresR56ES023591 · NIEHS · UNIVERSITY OF CALIFORNIA BERKELEY · PI BRADMAN, ASA · 2014 to 2014
$322k
NIEHS NIH HHS P01 ES009605NIEHS NIH HHS R56 ES023591
6 · The paper itself

Abstract

backgroundResidential proximity to agricultural pesticide use has been associated with neural tube defects and autism, but more subtle outcomes such as cognition have not been studied.

objectivesWe evaluated the relationship between prenatal residential proximity to agricultural use of potentially neurotoxic pesticides and neurodevelopment in 7-year-old children.

methodsParticipants included mothers and children (

resultsWe observed a decrease of 2.2 points [95% confidence interval (CI): −3.9, −0.5] in Full-Scale IQ and 2.9 points (95% CI: −4.4, −1.3) in Verbal Comprehension for each standard deviation increase in toxicity-weighted use of organophosphate pesticides. In separate models, we observed similar decrements in Full-Scale IQ with each standard deviation increase of use for two organophosphates (acephate and oxydemeton-methyl) and three neurotoxic pesticide groups (pyrethroids, neonicotinoids, and manganese fungicides).

conclusionsThis study identified potential relationships between maternal residential proximity to agricultural use of neurotoxic pesticides and poorer neurodevelopment in children. https://doi.org/10.1289/EHP504.

Indexed as

CaliforniaChildEnvironmental ExposureFemaleFungicides, IndustrialHumansInsecticidesIntelligenceMaleMaternal ExposureOrganophosphorus CompoundsPregnancyPrenatal Exposure Delayed EffectsResidence CharacteristicsFungicides, IndustrialInsecticidesOrganophosphorus Compounds

Identifiers

PMID28557711
PMCPMC5644974

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.