ArticleDevelopmental science2018
Salience network response to changes in emotional expressions of others is heightened during early adolescence: relevance for social functioning.
Article in Developmental science, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
34 citing papers in PubMed, 1 synthesis or guideline pooled it, 89 citations in OpenAlex.
- Social reward processing in depressed and healthy individuals across the lifespan: A systematic review and a preliminary coordinate-based meta-analysis of fMRI studies.Behavioural brain research · 2023Pooled it
- Acute tryptophan depletion balances altered resting-state functional connectivity of the salience network in female patients recovered from anorexia nervosa.Journal of psychiatry & neuroscience : JPNTrial
- Decoupling of amygdala-salience circuit associated with negative symptoms in adolescents with early-onset schizophrenia.Psychiatry and clinical neurosciences · 2026Article
- Changes in resting-state functional connectivity between large-scale brain networks after an intensive arts intervention for adolescents with depression.Translational psychiatry · 2026Article
- Knock down the first domino: in silico intervention for age-tailored prevention and treatment targets in adolescent mental health.European child & adolescent psychiatry · 2026Article
- Gestational PBDE concentrations and functional connectivity in adolescents: The HOME Study.International journal of hygiene and environmental health · 2026Article
- Loneliness and self-concept in the relations between Theory of Mind and social anhedonia in adolescents.Journal of research on adolescence : the official journal of the Society for Research on Adolescence · 2025Article
- Family criminal legal system exposure and early adolescents' pubertal development: the mediating role of family strain.American journal of epidemiology · 2025Article
- Latent Default Mode Network Connectivity Patterns: Associations With Sleep Health and Adolescent Psychopathology.Brain and behavior · 2025Article
- Testing an interpersonal risk pathway to suicidal ideation in adolescence: linking neural, psychological, and sociometric indices of socially relevant factors.Social cognitive and affective neuroscience · 2025Article
- Sensory driven neurophysiological mechanisms of concussion: a parsimonious and falsifiable theory.Frontiers in neurology · 2025Article
- Frontoparietal and salience network synchronizations during nonsymbolic magnitude processing predict brain age and mathematical performance in youth.Human brain mapping · 2024Article
- Adolescent neurocognitive development and decision-making abilities regarding gender-affirming care.Developmental cognitive neuroscience · 2024Review
- Higher Intersubject Variability in Neural Response to Narrative Social Stimuli Among Youth With Higher Social Anxiety.Journal of the American Academy of Child and Adolescent Psychiatry · 2024Article
- Strength and resilience of developing brain circuits predict adolescent emotional and stress responses during the COVID-19 pandemic.Cerebral cortex (New York, N.Y. : 1991) · 2024Article
- Neural sensitivity following stress predicts anhedonia symptoms: a 2-year multi-wave, longitudinal study.Translational psychiatry · 2024Article
- Differential processing of risk and reward in delinquent and non-delinquent youth.Social cognitive and affective neuroscience · 2023Article
- Neural Sensitivity following Stress Predicts Anhedonia Symptoms: A 2-Year Multi-wave, Longitudinal Study.Research square · 2023Article
- Cross-sectional and longitudinal neuroanatomical profiles of distinct clinical (adaptive) outcomes in autism.Molecular psychiatry · 2023Article
- Different functional connectivity optimal frequency in autism compared with healthy controls and the relationship with social communication deficits: Evidence from gene expression and behavior symptom analyses.Human brain mapping · 2023Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors at 2 institutions in 1 country.
Funding
Abstract
Adolescence is a unique developmental period when the salience of social and emotional information becomes particularly pronounced. Although this increased sensitivity to social and emotional information has frequently been considered with respect to risk behaviors and psychopathology, evidence suggests that increased adolescent sensitivity to social and emotional cues may confer advantages. For example, greater sensitivity to shifts in the emotions of others is likely to promote flexible and adaptive social behavior. In this study, a sample of 54 children and adolescents (age 8-19 years) performed a delayed match-to-sample task for emotional faces while undergoing fMRI scanning. Recruitment of the anterior cingulate and anterior insula when the emotion of the probe face did not match the emotion held in memory followed a quadratic developmental pattern that peaked during early adolescence. These findings indicate meaningful developmental variation in the neural mechanisms underlying sensitivity to changes in the emotional expressions. Across all participants, greater activation of this network for changes in emotional expression was associated with less social anxiety and fewer social problems. These results suggest that the heightened salience of social and emotional information during adolescence may confer important advantages for social behavior, providing sensitivity to others' emotions that facilitates flexible social responding.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.