ReviewJournal of veterinary internal medicine2017
Classification of Involuntary Movements in Dogs: Myoclonus and Myotonia.
Review in Journal of veterinary internal medicine, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
19 citing papers in PubMed, 36 citations in OpenAlex.
- Current knowledge of intermittent photic stimulation for electroencephalography in dogs.Journal of veterinary internal medicine · 2026Review
- Phenotypic characterization of presumptive propriospinal myoclonus in young dogs (2013-2025).Journal of veterinary internal medicine · 2026Article
- Myoclonus as a neurologic manifestation of hypoglycemia in dogs.Journal of veterinary internal medicine · 2026Article
- Myoclonus in geriatric dogs and its association with canine cognitive dysfunction: an online survey.Frontiers in veterinary science · 2026Article
- Evaluation of Cervical Myoclonus in Dogs with Spinal Diseases: 113 Cases (2014-2023).Animals : an open access journal from MDPI · 2025Article
- Spontaneous late-onset myoclonic epilepsy in cats: 15 cases (2015-2023).Journal of feline medicine and surgery · 2025Article
- Myotonia Congenita in Australian Merino Sheep with a Missense Variant inAnimals : an open access journal from MDPI · 2024Article
- Cushing's Myopathy in Dogs: Prevalence, Clinical Abnormalities, and Response to Treatment.Animals : an open access journal from MDPI · 2024Article
- Canine paroxysmal dyskinesia-a review.Frontiers in veterinary science · 2024Review
- Myoclonus in older Cavalier King Charles Spaniels.Journal of veterinary internal medicine · 2022Article
- International veterinary canine dyskinesia task force ECVN consensus statement: Terminology and classification.Journal of veterinary internal medicine · 2021Article
- Brain proton magnetic resonance spectroscopy findings in a Beagle dog with genetically confirmed Lafora disease.Journal of veterinary internal medicine · 2020Article
- Paradoxical pseudomyotonia in English Springer and Cocker Spaniels.Journal of veterinary internal medicine · 2020Article
- Myoclonus and hypercalcemia in a dog with poorly differentiated lymphoproliferative neoplasia.Journal of veterinary internal medicine · 2019Article
- Neuromyotonia in a horse.Journal of veterinary internal medicine · 2019Article
- Electrophysiological and histopathological findings of muscular disease suspected as myotonic dystrophy in a Shiba dog.The Journal of veterinary medical science · 2018Article
- Presumptive Acute Post-Hypoxic Myoclonus Following Return of Spontaneous Circulation in a Cat and a Dog.Journal of veterinary emergency and critical care (San Antonio, Tex. : 2001)Article
- Article
- Characteristics and clinical course of myoclonus in Cavalier King Charles Spaniels.Journal of veterinary internal medicineArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Myoclonus is a sudden brief, involuntary muscle jerk. Of all the movement disorders, myoclonus is the most difficult to encapsulate into any simple framework. On the one hand, a classification system is required that is clinically useful to aid in guiding diagnosis and treatment. On the other hand, there is need for a system that organizes current knowledge regarding biological mechanisms to guide scientific research. These 2 needs are distinct, making it challenging to develop a robust classification system suitable for all purposes. We attempt to classify myoclonus as "epileptic" and "nonepileptic" based on its association with epileptic seizures. Myotonia in people may be divided into 2 clinically and molecularly defined forms: (1) nondystrophic myotonias and (2) myotonic dystrophies. The former are a group of skeletal muscle channelopathies characterized by delayed skeletal muscle relaxation. Many distinct clinical phenotypes are recognized in people, the majority relating to mutations in skeletal muscle voltage-gated chloride (CLCN1) and sodium channel (SCN4A) genes. In dogs, myotonia is associated with mutations in CLCN1. The myotonic dystrophies are considered a multisystem clinical syndrome in people encompassing 2 clinically and molecularly defined forms designated myotonic dystrophy types 1 and 2. No mutation has been linked to veterinary muscular dystrophies. We detail veterinary examples of myotonia and attempt classification according to guidelines used in humans. This more precise categorization of myoclonus and myotonia aims to promote the search for molecular markers contributing to the phenotypic spectrum of disease. Our work aimed to assist recognition for these 2 enigmatic conditions.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.