Evidence map›Paper›PMID 28556921›Full record

ArticleImmunology2017

Membrane-bound Dickkopf-1 in Foxp3

Wook-Jin Chae, Jong-Hyun Park, Octavian Henegariu, Saliha Yilmaz, Liming Hao, Alfred L M Bothwell

Open access · bronzeAbstract read
In one paragraph

Article in Immunology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
1.1field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 20 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
  4. Article
  5. Article
  6. Article
  7. [Expression of plasma Dickkopf-1 in patients with rheumatoid arthritis and its correlation with peripheral blood T cell subsets].Beijing da xue xue bao. Yi xue ban = Journal of Peking University. Health sciences · 2020
    Article
  8. Treg regulation of the epithelial stem cell lineage.Journal of immunology and regenerative medicine · 2020
    Review
  9. Article
  10. Article
  11. Review
  12. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 2 countries.

Wook-Jin ChaeDepartment of Immunobiology, Yale University School of Medicine, New Haven, CT, USA.ORCID 0000-0003-0754-3561
Jong-Hyun ParkConvergence Research Centre for Diagnosis, Treatment and Care System of Dementia, KIST (Korea Institute of Science and Technology), Seoul, Korea.
Octavian HenegariuDepartment of Neurosurgery, Yale University School of Medicine, New Haven, CT, USA.
Saliha YilmazDepartment of Neurosurgery, Yale University School of Medicine, New Haven, CT, USA.
Liming HaoDepartment of Pathology, Yale University School of Medicine, New Haven, CT, USA.
Alfred L M BothwellDepartment of Immunobiology, Yale University School of Medicine, New Haven, CT, USA.
Yale University · USConvergence Research Center for Diagnosis Treatment and Care System of Dementia · KR

Funding

Yale Clinical and Translational Science Award (U Component)UL1TR001863 · NCATS · YALE UNIVERSITY · PI John H. Krystal, LUCILA OHNO-MACHADO · 2016 to 2026
$102.9M
Regulatory T Cell Control of Intestinal TumorigenesisR01CA168670 · NCI · YALE UNIVERSITY · PI BOTHWELL, ALFRED LM · 2014 to 2018
$2.1M
Regulatory T cell mediated control of colitis by Dkk1R21AI107957 · NIAID · YALE UNIVERSITY · PI BOTHWELL, ALFRED LM · 2013 to 2014
$443k
NCATS NIH HHS UL1 TR001863NCI NIH HHS R01 CA168670NIAID NIH HHS R21 AI107957
6 · The paper itself

Abstract

Induction of tolerance is a key mechanism to maintain or to restore immunological homeostasis. Here we show that Foxp3

Indexed as

Self ToleranceAdoptive TransferAnimalsAutoimmune DiseasesAutoimmunityCell MembraneCell ProliferationCHO CellsColitisColonCricetulusDisease Models, AnimalDNA-Binding ProteinsForkhead Transcription FactorsGenetic Predisposition to DiseaseIntercellular Signaling Peptides and ProteinsDkk1 protein, mouseDNA-Binding ProteinsForkhead Transcription FactorsFoxp3 protein, mouseIntercellular Signaling Peptides and ProteinsMitogen-Activated Protein KinasesRag2 protein, mouseautoimmune colitisDickkopf-1regulatory T cells

Identifiers

PMID28556921
PMCPMC5588763
OpenAlexW2618554165

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.