Evidence map›Paper›PMID 28556800›Full record

ReviewVaccines2017

Disease Prevention: An Opportunity to Expand Edible Plant-Based Vaccines?

Christopher Concha, Raúl Cañas, Johan Macuer, María José Torres, Andrés A Herrada, Fabiola Jamett, Cristian Ibáñez

Open access · goldAbstract readReview
In one paragraph

Review in Vaccines, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed
5.1field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 54 citations in OpenAlex.

  1. Review
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  5. Article
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  9. Review
  10. Article
  11. Review
  12. Review
  13. An AMA1/MSP1Molecular biotechnology · 2020
    Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Edible Vaccines: Promises and Challenges.Molecular biotechnology · 2020
    Review
  19. Review
  20. Mucosal vaccines and technology.Clinical and experimental immunology · 2019
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Christopher ConchaDepartamento de Biología Marina, Universidad Católica del Norte, Programa de Doctorado en Biología y Ecología Aplicada, Coquimbo 1780000, Chile. christopher.concha@ucn.cl.
Raúl CañasDepartamento de Ingeniería en Alimentos, Universidad de La Serena, Programa de Doctorado en Ingeniería en Alimentos y Bioprocesos, La Serena 1700000, Chile. raulhcs@gmail.com.
Johan MacuerDepartamento de Biología, Universidad de La Serena, Programa de Doctorado en Ingeniería en Alimentos y Bioprocesos, La Serena 1700000, Chile. johanmacuer@gmail.com.
María José TorresDepartamento de Ingeniería en Alimentos, Universidad de La Serena, Programa de Doctorado en Ingeniería en Alimentos y Bioprocesos, La Serena 1700000, Chile. mtorresossandon@gmail.com.
Andrés A HerradaFacultad de Salud, Universidad Autónoma de Chile, Talca 3460000, Chile. andresherradah@gmail.com.
Fabiola JamettDepartamento de Química, Universidad de La Serena, La Serena 1700000, Chile. fjamett@userena.cl.
Cristian IbáñezDepartamento de Biología, Universidad de La Serena, La Serena 1700000, Chile. cibanez@userena.cl.
University of La Serena · CLUniversidad Autónoma de Chile · CLUniversidad Católica del Norte · CL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The lethality of infectious diseases has decreased due to the implementation of crucial sanitary procedures such as vaccination. However, the resurgence of pathogenic diseases in different parts of the world has revealed the importance of identifying novel, rapid, and concrete solutions for control and prevention. Edible vaccines pose an interesting alternative that could overcome some of the constraints of traditional vaccines. The term "edible vaccine" refers to the use of edible parts of a plant that has been genetically modified to produce specific components of a particular pathogen to generate protection against a disease. The aim of this review is to present and critically examine "edible vaccines" as an option for global immunization against pathogenic diseases and their outbreaks and to discuss the necessary steps for their production and control and the list of plants that may already be used as edible vaccines. Additionally, this review discusses the required standards and ethical regulations as well as the advantages and disadvantages associated with this powerful biotechnology tool.

Indexed as

disease outbreaksedible vaccinefood biotechnologygenetic modificationimmunogenicitymedicinal food

Identifiers

PMID28556800
PMCPMC5492011
OpenAlexW2618941283

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.