Evidence map›Paper›PMID 28556623›Full record

ArticleCancer medicine2017

Ultrasonography-driven combination antibiotic therapy with tigecycline significantly increases survival among patients with neutropenic enterocolitis following cytarabine-containing chemotherapy for the remission induction of acute myeloid leukemia.

Novella Pugliese, Paola Salvatore, Dora Vita Iula, Maria Rosaria Catania, Federico Chiurazzi, Roberta Della Pepa, Claudio Cerchione, Marta Raimondo, Claudia Giordano, Luigia Simeone and 3 more

Open access · goldAbstract read
In one paragraph

Article in Cancer medicine, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed, 1 pooled it
0.7field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 1 synthesis or guideline pooled it, 18 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Epidemiology, Risk Factors, and Outcomes of Neutropenic Enterocolitis in Onco-Hematological Patients According to Chemotherapy Regimen.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2026
    Article
  4. Review
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Chemotherapy-related infectious complications in patients with Hematologic malignancies.Journal of research in medical sciences : the official journal of Isfahan University of Medical Sciences · 2018
    Article
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 1 institution in 1 country.

Novella PuglieseDepartments of Clinical Medicine and Surgery, Federico II University Medical School, Naples, Italy.ORCID http://orcid.org/0000-0002-2714-5109
Paola SalvatoreMolecular Medicine and Medical Biotechnology, Federico II University Medical School, Naples, Italy.
Dora Vita IulaMolecular Medicine and Medical Biotechnology, Federico II University Medical School, Naples, Italy.
Maria Rosaria CataniaMolecular Medicine and Medical Biotechnology, Federico II University Medical School, Naples, Italy.
Federico ChiurazziDepartments of Clinical Medicine and Surgery, Federico II University Medical School, Naples, Italy.
Roberta Della PepaDepartments of Clinical Medicine and Surgery, Federico II University Medical School, Naples, Italy.
Claudio CerchioneDepartments of Clinical Medicine and Surgery, Federico II University Medical School, Naples, Italy.
Marta RaimondoDepartments of Clinical Medicine and Surgery, Federico II University Medical School, Naples, Italy.
Claudia GiordanoDepartments of Clinical Medicine and Surgery, Federico II University Medical School, Naples, Italy.
Luigia SimeoneDepartments of Clinical Medicine and Surgery, Federico II University Medical School, Naples, Italy.
Simona CarusoDepartments of Clinical Medicine and Surgery, Federico II University Medical School, Naples, Italy.
Fabrizio PaneDepartments of Clinical Medicine and Surgery, Federico II University Medical School, Naples, Italy.
Marco PicardiAdvanced Biomedical Sciences, Federico II University Medical School, Naples, Italy.
Federico II University Hospital · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Neutropenic enterocolitis (NEC) is an abdominal infection reported primarily in patients with acute myeloid leukemia (AML) following chemotherapy, especially cytarabine, a notable efficacious cytotoxic agent for AML remission. Specific data regarding the impact of different cytarabine schedules and/or antibacterial regimens for NEC are sparse. The aim of the study was to identify the predictors of outcome within 30 days of NEC onset. NEC episodes were retrospectively pinpointed among 440 patients with newly diagnosed AML hospitalized in our Institution, over a 10-year period, for receiving chemotherapy protocols with 100-6000 mg/m

Indexed as

AdultAgedAnti-Bacterial AgentsAntineoplastic Combined Chemotherapy ProtocolsCytarabineDisease ManagementDrug Therapy, CombinationEnterocolitis, NeutropenicFemaleHumansLeukemia, Myeloid, AcuteMaleMiddle AgedMinocyclineMortalityRemission InductionAnti-Bacterial AgentsCytarabineMinocyclineTigecyclineAcute myeloid leukemiacytarabineneutropenic enterocolitistigecycline

Identifiers

PMID28556623
PMCPMC5504336
OpenAlexW2617371007

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.