Evidence map›Paper›PMID 28555838›Full record

ArticleEuropean journal of immunology2017

Spontaneous CD4

Hayden Pearce, Paul Hutton, Shalini Chaudhri, Emilio Porfiri, Prashant Patel, Richard Viney, Paul Moss

Open access · hybridAbstract read
In one paragraph

Article in European journal of immunology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
0.6field-weighted citation impact, top 36% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 22 citations in OpenAlex.

  1. Article
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  3. Review
  4. Neoantigen-specific CD4Journal for immunotherapy of cancer · 2023
    Article
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  7. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Hayden PearceInstitute of Immunology and Immunotherapy, College of Medical and Dental Sciences, University of Birmingham, Birmingham, UK.ORCID 0000-0002-8380-8122
Paul HuttonUniversity Hospitals NHS Foundation Trust, Birmingham, UK.
Shalini ChaudhriUniversity Hospitals NHS Foundation Trust, Birmingham, UK.
Emilio PorfiriUniversity Hospitals NHS Foundation Trust, Birmingham, UK.
Prashant PatelUniversity Hospitals NHS Foundation Trust, Birmingham, UK.
Richard VineyUniversity Hospitals NHS Foundation Trust, Birmingham, UK.
Paul MossInstitute of Immunology and Immunotherapy, College of Medical and Dental Sciences, University of Birmingham, Birmingham, UK.
University Hospitals Birmingham NHS Foundation Trust · GBNIHR Birmingham Biomedical Research Centre · GB

Funding

Medical Research Council
6 · The paper itself

Abstract

Cancer/testis antigen (CTAg) expression is restricted to spermatogenic cells in an immune-privileged site within the testis. However, these proteins are expressed aberrantly by malignant cells and T-cell responses against CTAgs develop in many cancer patients. We investigated the prevalence, magnitude and phenotype of CTAg-specific T cells in the blood of patients with testicular germ cell tumors (TGCTs). CD8

Indexed as

AdolescentAdultAntigens, NeoplasmCD4-Positive T-LymphocytesCD8-Positive T-LymphocytesEnzyme-Linked Immunospot AssayHumansImmunologic MemoryInterferon-gammaLymphocyte ActivationMaleMembrane ProteinsNeoplasms, Germ Cell and EmbryonalOrchiectomyPeptidesTesticular NeoplasmsAntigens, NeoplasmCTAG1B protein, humanInterferon-gammaMembrane ProteinsPeptidesCancer testis antigensMAGET cellsTesticular cancerTumor immunology

Identifiers

PMID28555838
PMCPMC5519936
OpenAlexW2617403669

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.