Evidence map›Paper›PMID 28555324›Full record

ReviewJournal of endocrinological investigation2017

Low maternal circulating levels of vitamin D as potential determinant in the development of gestational diabetes mellitus.

S Triunfo, A Lanzone, P G Lindqvist

Abstract readReview
PubMed Publisher
In one paragraph

Review in Journal of endocrinological investigation, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed
7.2field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 54 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Article
  6. Article
  7. Review
  8. Article
  9. Article
  10. Article
  11. The role of vitamin D in perinatology. An up-to-date review.Archives of medical science : AMS · 2021
    Article
  12. Article
  13. Article
  14. Vitamin D and Gestational Diabetes Mellitus: Is There a Link?Antioxidants (Basel, Switzerland) · 2019
    Review
  15. Article
  16. Pregnancy in Thalassemia.Mediterranean journal of hematology and infectious diseases · 2019
    Review
  17. Observational
  18. Article
  19. Observational
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 3 institutions in 3 countries.

S TriunfoBCNatal-Barcelona Center for Maternal-Fetal and Neonatal Medicine, University of Barcelona, Sabino de Arana 1, 08028, Barcelona, Spain. triunfo@clinic.ub.es.
A LanzoneDepartment of Obstetrics and Gynecology, Catholic University of the Sacred Heart, Rome, Italy.
P G LindqvistDepartment of Obstetrics and Gynecology, CLINTEC Karolinska University Hospital, Stockholm, Sweden.
Karolinska University Hospital · SEUniversità Cattolica del Sacro Cuore · ITUniversitat de Barcelona · ES

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Gestational diabetes mellitus (GDM), defined as any glucose intolerance with the onset or first recognition during pregnancy, is characterized by rising incidence, fostered by the worldwide increase of pathological nutritional status from young age. Clinical research has intended to identify potential risk factors, suggested improvements in screening strategies, and recommended the combination between promotion of an appropriate lifestyle before and during pregnancy and selected therapeutic approaches. Preventing pathological hyperglycemia could have several benefits, ranging from clinical side (reduction in the risk of adverse perinatal and long-term sequelae) to financial side (cost reduction to healthcare systems). Among risk factors recognized, deficiency in 25-hydroxyvitamin D [25(OH)D], already acknowledged as involved in calcium homeostasis, pathogenesis of cardiovascular, oncological, infective and immunity diseases, could predispose to the development of both type 1 and 2 diabetes, modifying the activity of pancreatic β-cells vitamin D (VD) receptor. In pregnant women, lower 25(OH)D concentrations have been suggested to present an inverse association with maternal glycaemia, insulin resistance, and increased risk of GDM. In spite of growing body of evidence, there is not full agreement on the therapeutic association between GDM based on VD deficiency and 25(OH)D supplementation. In the attempt to bring up-to-date the role of low VD levels on subsequent development of GDM, this narrative review, based on medium-high-quality randomized clinical trials, systematic reviews, and meta-analysis published in last decade, has a twofold purpose: firstly, to elucidate the relationship between maternal VD status and GDM; and secondly, to illuminate the impact of VD supplementation on GDM onset.

Indexed as

BiomarkersDiabetes, GestationalFemaleHumansPregnancyRisk FactorsVitamin DVitamin D DeficiencyVitaminsBiomarkersVitamin DVitaminsBeneficial effectsGestational diabetesSupplementationVitamin D

Identifiers

PMID28555324
OpenAlexW2618939799

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.