ArticlePediatric radiology2017
Assessment of airway compression on chest radiographs in children with pulmonary tuberculosis.
Article in Pediatric radiology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
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Who cites it
12 citing papers in PubMed, 14 citations in OpenAlex.
- Computer-aided detection for radiological disease severity classification on chest radiograph in children with intra-thoracic tuberculosis.PLOS global public health · 2026Article
- Multi-view deep learning framework for the detection of chest X-rays compatible with pediatric pulmonary tuberculosis.Nature communications · 2025Article
- Diagnostic performance of chest radiography for pediatric tuberculosis across high- and low-burden settings.Frontiers in pediatrics · 2025Article
- Comparison of chest radiographs against minimum intensity projection reconstruction computed tomography scans for detection of airway stenosis in children with lymphobronchial tuberculosis.Pediatric radiology · 2024Article
- Comparison of chest ultrasound features to chest radiography in the diagnosis for pediatric tuberculosis: a cross-sectional study.The Pan African medical journal · 2024Article
- Imaging recommendations and algorithms for pediatric tuberculosis: part 1-thoracic tuberculosis.Pediatric radiology · 2023Review
- Changes in the role of chest radiographs for diagnosing and managing children with tuberculosis: the 2022 World Health Organization consolidated guidelines on tuberculosis.Pediatric radiology · 2023Article
- The Diagnostic Accuracy of Chest Radiographic Features for Pediatric Intrathoracic Tuberculosis.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2022Article
- Reproducibility of a protocol for standardized reading of chest X-rays of children household contact of patients with tuberculosis.BMC pediatrics · 2022Article
- Study of the association of interferon-γ gene polymorphisms and Th1/Th2 balance in tuberculosis susceptibility.American journal of translational research · 2021Article
- Chest ultrasound compared to chest X-ray for pediatric pulmonary tuberculosis.Pediatric pulmonology · 2019Article
- Technical aspects of mediastinal ultrasound for pediatric pulmonary tuberculosis.Pediatric radiology · 2017Review
Corrections and comments
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Authors and funding
4 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundBecause small, pliable paediatric airways are easily compressed by enlarged lymph nodes, detection of radiographic airway compression might be an objective criterion for diagnosing pulmonary tuberculosis.
objectiveTo investigate the frequency and inter-observer agreement of airway compression on chest radiographs in children with pulmonary tuberculosis compared to those with a different lower respiratory tract infection. MATERIALS AND
methodsChest radiographs of children with suspected pulmonary tuberculosis were read by two readers according to a standardised format and a third reader when there was disagreement. Radiographs of children with proven pulmonary tuberculosis were compared to those with a different lower respiratory tract infection. We evaluated frequency and location of radiographic airway compression. Findings were correlated with human immunodeficiency virus (HIV) status and age. We assessed inter-observer agreement using kappa statistics.
resultsWe reviewed radiographs of 505 children (median age 25.9 months, interquartile range [IQR] 14.3-62.2). Radiographic airway compression occurred in 54/188 (28.7%) children with proven pulmonary tuberculosis and in 24/317 (7.6%) children with other types of lower respiratory tract infection (odds ratio [OR] 4.9; 95% confidence interval [CI] 2.9-8.3). A higher frequency of radiographic airway compression occurred in infants (22/101, or 21.8%) compared to older children (56/404, or 13.9%; OR 1.7; 95% CI 1.0-3.0). We found no association between airway compression and HIV infection. Inter-observer agreement ranged from none to fair (kappa of 0.0-0.4).
conclusionThere is a strong association between airway compression on chest radiographs and confirmed pulmonary tuberculosis. However this finding's clinical use as an objective criterion for diagnosis of pulmonary tuberculosis in children is limited by poor inter-observer agreement.
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