ArticleProbiotics and antimicrobial proteins2017
A Simple Method for the Purification of Nisin.
Article in Probiotics and antimicrobial proteins, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
12 citing papers in PubMed, 32 citations in OpenAlex.
- A truncated nisin variant, lipidated at its C-terminus, displays improved stability and increased antibacterial activity against methicillin-resistantRSC chemical biology · 2026Article
- Enhancing the Antitumor Efficacy of Nisin Through Advanced Nanosystems: A Systematic Review of In Vitro Studies.Pharmaceuticals (Basel, Switzerland) · 2026Review
- Valorisation of acid whey permeate for high-purity nisin Z production using artisanal Lactococcus lactis isolates.BMC microbiology · 2025Article
- A Bifidobacterium Strain with Antibacterial Activity, Its Antibacterial Characteristics and In Vitro Probiotics Studies.Microorganisms · 2025Article
- Nisin Purification from a Cell-Free Supernatant by Electrodialysis in a Circular Economy Framework.Membranes · 2023Article
- Modulation of the gut microbiome with nisin.Scientific reports · 2023Article
- Combination Treatment for Inhibition of the Growth ofAntibiotics (Basel, Switzerland) · 2022Article
- Susceptibility to Nisin, Bactofencin, Pediocin and Reuterin of Multidrug ResistantAntibiotics (Basel, Switzerland) · 2021Article
- Comparison of Different Nisin Separation and Concentration Methods: Industrial and Cost-Effective Perspectives.Probiotics and antimicrobial proteins · 2020Article
- Synergistic Inhibition by Bacteriocin and Bacteriophage againstFood science of animal resources · 2019Article
- Partial purification, characterization and mode of action of bacteriocins produced by three strains ofJournal of food science and technology · 2019Article
- Oral Delivery of Nisin in Resistant Starch Based Matrices Alters the Gut Microbiota in Mice.Frontiers in microbiology · 2018Article
Corrections and comments
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Authors and funding
7 authors at 3 institutions in 1 country.
Funding
Abstract
Nisin, an antimicrobial peptide showing activity against a broad range of Gram-positive bacteria, is widely used as a food preservative and has potential as a therapeutic for a range of infectious diseases. Here, we present a simple purification method, based on a salting-out approach, which can produce a powder containing ∼33% nisin, from a nisin-producing culture in a whey permeate-based medium. This process removes over 99% of the lactic acid, NaCl, lactose and non-nisin proteins from the cell-free culture supernatant. The approach can also enrich a commonly used commercial nisin preparation over 30-fold to a purity of ∼58%. These are higher purities than comparable published methods. The simplicity of this approach facilitates its use in research and also its scale-up.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.