Evidence map›Paper›PMID 28555174›Full record

ArticleFrontiers in cellular and infection microbiology2017

The ATP-Dependent Protease ClpP Inhibits Biofilm Formation by Regulating Agr and Cell Wall Hydrolase Sle1 in

Qian Liu, Xing Wang, Juanxiu Qin, Sen Cheng, Won-Sik Yeo, Lei He, Xiaowei Ma, Xiaoyun Liu, Min Li, Taeok Bae

Open access · goldAbstract read
In one paragraph

Article in Frontiers in cellular and infection microbiology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers.

0numbers the graph read from it
0cells of the map it votes in
33citing papers in PubMed
1.7field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

33 citing papers in PubMed, 55 citations in OpenAlex.

  1. Article
  2. Polydatin as a natural ClpP modulator for combating methicillin-resistantFrontiers in cellular and infection microbiology · 2026
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  5. Frontiers in microbiology · 2025
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  6. Machine learning and network analysis with focus on the biofilm inComputational and structural biotechnology journal · 2024
    Article
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  8. Chicken Juice EnhancesFoods (Basel, Switzerland) · 2024
    Article
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  10. Review
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  13. Review
  14. Article
  15. Targeting the Achilles' Heel of Multidrug-ResistantInternational journal of molecular sciences · 2022
    Article
  16. Review
  17. Review
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 5 institutions in 2 countries.

Qian LiuDepartment of Laboratory Medicine, School of Medicine, Ren Ji Hospital, Shanghai Jiao Tong UniversityShanghai, China.
Xing WangDepartment of Laboratory Medicine, Shanghai Children's Medical Center, School of Medicine, Shanghai Jiao Tong UniversityShanghai, China.
Juanxiu QinDepartment of Laboratory Medicine, School of Medicine, Ren Ji Hospital, Shanghai Jiao Tong UniversityShanghai, China.
Sen ChengInstitute of Analytical Chemistry and Synthetic and Functional Biomolecules Center, College of Chemistry and Molecular Engineering, Peking UniversityBeijing, China.
Won-Sik YeoDepartment of Microbiology and Immunology, Indiana University School of Medicine-NorthwestGary, IN, USA.
Lei HeDepartment of Laboratory Medicine, School of Medicine, Ren Ji Hospital, Shanghai Jiao Tong UniversityShanghai, China.
Xiaowei MaDepartment of Laboratory Medicine, School of Medicine, Ren Ji Hospital, Shanghai Jiao Tong UniversityShanghai, China.
Xiaoyun LiuInstitute of Analytical Chemistry and Synthetic and Functional Biomolecules Center, College of Chemistry and Molecular Engineering, Peking UniversityBeijing, China.
Min LiDepartment of Laboratory Medicine, School of Medicine, Ren Ji Hospital, Shanghai Jiao Tong UniversityShanghai, China.
Taeok BaeDepartment of Microbiology and Immunology, Indiana University School of Medicine-NorthwestGary, IN, USA.
Renji Hospital · CNIndiana University Northwest · USShanghai Jiao Tong University · CNKing University · USPeking University · CN

Funding

Development of anti-virulence drugs by targeting the SaeRS two component system of Staphylococcus aureusR21AI121664 · NIAID · INDIANA UNIVERSITY INDIANAPOLIS · PI BAE, TAEOK · 2016 to 2017
$374k
NIAID NIH HHS R21 AI121664
6 · The paper itself

Abstract

Biofilm causes hospital-associated infections on indwelling medical devices. In

Indexed as

AnimalsAutolysisBacterial ProteinsBiofilmsCell WallDisease Models, AnimalEndopeptidase ClpGene Expression Regulation, BacterialGenes, BacterialHydrolasesMaleMiceMice, Inbred BALB CMutationStaphylococcus aureusTrans-ActivatorsAgr protein, Staphylococcus aureusBacterial ProteinsEndopeptidase ClpHydrolasesTrans-ActivatorsAgrbiofilmcell wall hydrolysisproteolysis systemStaphylococcus aureus

Identifiers

PMID28555174
PMCPMC5430930
OpenAlexW2614936755

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.