Evidence map›Paper›PMID 28555162›Full record

ArticleOxidative medicine and cellular longevity2017

Red Yeast Rice Protects Circulating Bone Marrow-Derived Proangiogenic Cells against High-Glucose-Induced Senescence and Oxidative Stress: The Role of Heme Oxygenase-1.

Jung-Tung Liu, Huey-Yi Chen, Wen-Chi Chen, Kee-Ming Man, Yung-Hsiang Chen

Open access · hybridAbstract read
In one paragraph

Article in Oxidative medicine and cellular longevity, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed, 1 pooled it
2.6field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 1 synthesis or guideline pooled it, 22 citations in OpenAlex.

  1. Pooled it
  2. Clinical pharmacology : advances and applications · 2025
    Review
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  4. Comparative Effects of Monascin and Monascinol Produced byJournal of fungi (Basel, Switzerland) · 2024
    Article
  5. Review
  6. Review
  7. Article
  8. Review
  9. HO-1 in Bone Biology: Potential Therapeutic Strategies for Osteoporosis.Frontiers in cell and developmental biology · 2021
    Review
  10. Article
  11. Looking for immortality: Review of phytotherapy for stem cell senescence.Iranian journal of basic medical sciences · 2020
    Review
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 4 institutions in 2 countries.

Jung-Tung LiuSchool of Medicine, College of Medicine, Chung Shan Medical University, Taichung 402, Taiwan.ORCID 0000-0002-5865-6753
Huey-Yi ChenGraduate Institute of Integrated Medicine, College of Chinese Medicine, Research Center for Chinese Medicine & Acupuncture, China Medical University, Taichung 404, Taiwan.
Wen-Chi ChenGraduate Institute of Integrated Medicine, College of Chinese Medicine, Research Center for Chinese Medicine & Acupuncture, China Medical University, Taichung 404, Taiwan.
Kee-Ming ManDepartments of Obstetrics and Gynecology, Urology, Anesthesiology, and Medical Research, China Medical University Hospital, Taichung 404, Taiwan.
Yung-Hsiang ChenGraduate Institute of Integrated Medicine, College of Chinese Medicine, Research Center for Chinese Medicine & Acupuncture, China Medical University, Taichung 404, Taiwan.ORCID 0000-0002-8756-5113
China Medical University · TWAsia University · TWChung Shan Medical University Hospital · TWDayeh University · TW

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The inflammation and oxidative stress of bone marrow-derived proangiogenic cells (PACs), also named endothelial progenitor cells, triggered by hyperglycemia contributes significantly to vascular dysfunction. There is supporting evidence that the consumption of red yeast rice (RYR;

Indexed as

Biological ProductsBone Marrow CellsCellular SenescenceDiabetic AngiopathiesGlucoseHeme Oxygenase-1HumansOxidative StressReactive Oxygen SpeciesBiological ProductsGlucoseHeme Oxygenase-1HMOX1 protein, humanReactive Oxygen Speciesred yeast rice

Identifiers

PMID28555162
PMCPMC5438855
OpenAlexW2611672758

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.