Evidence map›Paper›PMID 28555055›Full record

ReviewInternational journal of molecular sciences2017

The Methods of Choice for Extracellular Vesicles (EVs) Characterization.

Rafal Szatanek, Monika Baj-Krzyworzeka, Jakub Zimoch, Malgorzata Lekka, Maciej Siedlar, Jarek Baran

Registry-linked trialAbstract readReview
In one paragraph

Review in International journal of molecular sciences, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07273643 (Characterization of Extracellular Vesicles From the Cord Blood of Extremely Preterm New Borns and Their Correlation With Severe Morbidity and Mortality), which is not on this map. Cited by 307 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
307citing papers in PubMed, 3 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07273643 recruitingnot on this mapstarted 2026, after this paper: background citation

Characterization of Extracellular Vesicles From the Cord Blood of Extremely Preterm New Borns and Their Correlation With Severe Morbidity and Mortality

Typeobservational_patient_registrySponsorUniversity Hospital, MontpellierRan2026 to 2027Enrolled30ConditionsIntraventricular Hemorrhage, Pulmonary Hemorrhage, Death, ELGAN (22-28SA)ArmsVenous Cord blood sample, Arterial cord blood sample
3 · Its place in the literature

Who cites it

307 citing papers in PubMed, 3 syntheses or guidelines pooled it.

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247 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Rafal SzatanekDepartment of Clinical Immunology, Institute of Paediatrics, Jagiellonian University Medical College, 30-663 Krakow, Poland. rafal.szatanek@uj.edu.pl.
Monika Baj-KrzyworzekaDepartment of Clinical Immunology, Institute of Paediatrics, Jagiellonian University Medical College, 30-663 Krakow, Poland. mibaj@cyf-kr.edu.pl.
Jakub ZimochTissue Biology Research Unit, Department of Surgery, University Children's Hospital Zurich, 8032 Zurich, Switzerland. jakub.zimoch@kispi.uzh.ch.
Malgorzata LekkaDepartment of Research of Biophysical Microstructure, Institute of Nuclear Physics Polish Academy of Sciences, 31-342 Krakow, Poland. malgorzata.lekka@gmail.com.
Maciej SiedlarDepartment of Clinical Immunology, Institute of Paediatrics, Jagiellonian University Medical College, 30-663 Krakow, Poland. misiedla@cyf-kr.edu.pl.
Jarek BaranDepartment of Clinical Immunology, Institute of Paediatrics, Jagiellonian University Medical College, 30-663 Krakow, Poland. mibaran@cyf-kr.edu.pl.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In recent years, extracellular vesicles (EVs) have become a subject of intense study. These membrane-enclosed spherical structures are secreted by almost every cell type and are engaged in the transport of cellular content (cargo) from parental to target cells. The impact of EVs transfer has been observed in many vital cellular processes including cell-to-cell communication and immune response modulation; thus, a fast and precise characterization of EVs may be relevant for both scientific and diagnostic purposes. In this review, the most popular analytical techniques used in EVs studies are presented with the emphasis on exosomes and microvesicles characterization.

Indexed as

AnimalsCell-Derived MicroparticlesCryoelectron MicroscopyExosomesExtracellular VesiclesFlow CytometryHumansMicroscopy, Atomic ForceMicroscopy, Electron, Transmissionatomic force microscopy (AFM)cryo-electron microscopy (Cryo-EM)dynamic light scattering (DLS)exosomesextracellular vesicles (EVs)flow cytometrymicrovesicles (MVs)nanoparticle tracking analysis (NTA)stimulated emission depletion microscopy (STED)transmission electron microscopy (TEM)

Identifiers

PMID28555055
PMCPMC5485977

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.