Evidence map›Paper›PMID 28555019›Full record

ArticleInternational journal of molecular sciences2017

Mutual Regulation of NOD2 and RIG-I in Zebrafish Provides Insights into the Coordination between Innate Antibacterial and Antiviral Signaling Pathways.

Li Nie, Xiao-Xiao Xu, Li-Xin Xiang, Jian-Zhong Shao, Jiong Chen

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.1field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 19 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

Li NieLaboratory of Biochemistry and Molecular Biology, School of Marine Sciences, Ningbo University, Ningbo 315211, China. nieli@nbu.edu.cn.
Xiao-Xiao XuCollege of Life Sciences, Zhejiang University, Hangzhou 310058, China. shawnlucy@zju.edu.cn.
Li-Xin XiangCollege of Life Sciences, Zhejiang University, Hangzhou 310058, China. xianglx.zju@gmail.com.
Jian-Zhong ShaoCollege of Life Sciences, Zhejiang University, Hangzhou 310058, China. shaojz@zju.edu.cn.
Jiong ChenLaboratory of Biochemistry and Molecular Biology, School of Marine Sciences, Ningbo University, Ningbo 315211, China. chenjiong@nbu.edu.cn.
Ningbo University · CNZhejiang University · CNQingdao National Laboratory for Marine Science and Technology · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Nucleotide-binding oligomerization domain-containing protein 2 (NOD2) and retinoic acid-inducible gene I (RIG-I) are two important cytosolic pattern recognition receptors (PRRs) in the recognition of pathogen-associated molecular patterns (PAMPs), initiating innate antibacterial and antiviral signaling pathways. However, the relationship between these PRRs, especially in teleost fish models, is rarely reported. In this article, we describe the mutual regulation of zebrafish NOD2 (

Indexed as

AnimalsAnti-Bacterial AgentsAntiviral AgentsDEAD Box Protein 58HEK293 CellsHumansImmunity, InnateNF-kappa BNod2 Signaling Adaptor ProteinReceptors, ImmunologicSignal TransductionZebrafishAnti-Bacterial AgentsAntiviral AgentsDEAD Box Protein 58NF-kappa BNod2 Signaling Adaptor ProteinReceptors, ImmunologicRIGI protein, humanIFN signalingnegative mutual regulationNF-κB signalingzebrafish NOD2zebrafish RIG-I

Identifiers

PMID28555019
PMCPMC5485971
OpenAlexW2618854705

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.