Evidence map›Paper›PMID 28555011›Full record

Trial reportNutrients2017

The IL-6 Gene Promoter SNP and Plasma IL-6 in Response to Diet Intervention.

Brinda K Rana, Shirley W Flatt, Dennis D Health, Bilge Pakiz, Elizabeth L Quintana, Loki Natarajan, Cheryl L Rock

Abstract readRandomized Controlled Trial
In one paragraph

Trial report in Nutrients, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed.

  1. Article
  2. Review
  3. Review
  4. Review
  5. Article
  6. Article
  7. Article
  8. Hallmarks of Severe COVID-19 Pathogenesis:Frontiers in immunology · 2022
    Review
  9. Genes · 2021
    Article
  10. Article
  11. Article
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Brinda K RanaDepartment of Psychiatry, School of Medicine, University of California, San Diego, La Jolla, CA 92093-0738, USA. bkrana@ucsd.edu.
Shirley W FlattDepartment of Family Medicine and Public Health, School of Medicine, University of California, San Diego, La Jolla, CA 92093-0901, USA. sflatt@ucsd.edu.
Dennis D HealthDepartment of Family Medicine and Public Health, School of Medicine, University of California, San Diego, La Jolla, CA 92093-0901, USA. dheath@ucsd.edu.
Bilge PakizDepartment of Family Medicine and Public Health, School of Medicine, University of California, San Diego, La Jolla, CA 92093-0901, USA. bpakiz@ucsd.edu.
Elizabeth L QuintanaDepartment of Family Medicine and Public Health, School of Medicine, University of California, San Diego, La Jolla, CA 92093-0901, USA. Elquintana@ucsd.edu.
Loki NatarajanDepartment of Family Medicine and Public Health, School of Medicine, University of California, San Diego, La Jolla, CA 92093-0901, USA. lnatarajan@ucsd.edu.
Cheryl L RockDepartment of Family Medicine and Public Health, School of Medicine, University of California, San Diego, La Jolla, CA 92093-0901, USA. clrock@ucsd.edu.

Funding

Two-Spirit Films in Indigenous Cancer HealthP30CA016056 · NCI · ROSWELL PARK CANCER INSTITUTE CORP · PI MARK G FRATTINI · 1985 to 2026
$116.6M
UCSD Biorepository Shared ResourceU54CA155435 · NCI · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI PATTERSON, RUTH E · 2011 to 2015
$9.1M
NCI NIH HHS P30 CA016056NCI NIH HHS U54 CA155435
6 · The paper itself

Abstract

We recently reported that interleukin-6 (IL-6), an inflammatory marker associated with breast pathology and the development of breast cancer, decreases with diet intervention and weight loss in both insulin-sensitive and insulin-resistant obese women. Here, we tested whether an individual's genotype at an

Indexed as

Diet, Fat-RestrictedPolymorphism, Single NucleotidePromoter Regions, GeneticAdultBiomarkersBody Mass IndexDietary CarbohydratesDietary FatsFemaleHumansInterleukin-6Middle AgedObesityOverweightWeight LossYoung AdultBiomarkersDietary CarbohydratesDietary FatsIL6 protein, humanInterleukin-6BMIdiet interventionIL-6rs1800795walnut

Identifiers

PMID28555011
PMCPMC5490531

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.