ArticleTravel medicine and infectious disease
Severe Plasmodium falciparum malaria in the intensive care unit: A 6-year experience in Milano, Italy.
Article in Travel medicine and infectious disease. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
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Who cites it
9 citing papers in PubMed.
- Deep Learning-Based Malaria Parasite Image Classification on Real Microscopy Data.Infectious disease reports · 2026Article
- Two Cases of Malaria-Associated Acute Respiratory Distress Syndrome and Severe Pulmonary Complications From Plasmodium falciparum in Tanzania.The American journal of case reports · 2026Article
- Weakening TPR-MBER correlation: Marker of success in India's malaria elimination progress.Bioinformation · 2026Article
- Malaria: 11-Year Experience With Imported Cases at a German University Hospital and Epidemiological Trends Amid the COVID-19 Pandemic.Journal of parasitology research · 2026Article
- The blood purification therapy-based strategy effectively rescued the severe falciparum malaria patient experiencing cytokine storm-driven MODS.Frontiers in cellular and infection microbiology · 2025Article
- Imported malaria definition and minimum data for surveillance.Scientific reports · 2022Review
- Changes in the clinical presentation and outcomes of patients treated for severe malaria in a referral French university intensive care unit from 2004 to 2017.Annals of intensive care · 2020Article
- Article
- Genetic diversity and transmissibility of imported Plasmodium vivax in Qatar and three countries of origin.Scientific reports · 2018Article
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23 authors.
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No grant is acknowledged in the PubMed record.
Abstract
backgroundSevere imported Plasmodium falciparum malaria is a potentially life-threatening disease with a reported mortality rate of 5-10% when patients are admitted to the Intensive Care Unit.
methodsTo retrospectively review the clinical aspects, the value of severity predictive scores and the management of patients with severe P. falciparum malaria admitted to an ICU in Milano, Italy between January 2010 and December 2015.
resultsTwelve patients were included: seven were male and five female with a median age of 43 years. All were initially treated with intravenous quinine. Median parasitaemia upon admission was 14,5% (range 1-20%). At the time of ICU admission, 3 patients (25%) had 5 or more World Health Organization criteria for severe malaria while another 6 of them developed one or more of the latter during their stay in ICU. Five required mechanical ventilation because of respiratory failure due to ARDS. Four patients required renal replacement therapy. Three patients underwent blood exchange transfusion. All patients survived.
conclusionsOur retrospective evaluation of adults patients admitted to the ICU with severe imported P. falciparum malaria demonstrated a favourable outcome. Severity predictive scores currently in use probably overestimate the risk of malaria mortality in patients treated in health care systems of high income countries.
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