Evidence map›Paper›PMID 28554250›Full record

ArticleMolecular pain

Resveratrol-decreased hyperalgesia mediated by the P2X

Bing Wu, Yucheng Ma, Zhihua Yi, Shuangmei Liu, Shenqiang Rao, Lifang Zou, Shouyu Wang, Yun Xue, Tianyu Jia, Shanhong Zhao and 4 more

Open access · goldAbstract read
In one paragraph

Article in Molecular pain. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed, 1 pooled it
1.7field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 1 synthesis or guideline pooled it, 27 citations in OpenAlex.

  1. Pooled it
  2. Glial cells in neuropathic pain.Physiological reviews · 2026
    Review
  3. Review
  4. Review
  5. Article
  6. Review
  7. Neuropathogenesis of HIV and emerging therapeutic targets.Expert opinion on therapeutic targets · 2022
    Review
  8. Review
  9. Review
  10. Article
  11. Review
  12. Article
  13. Recent development in antihyperalgesic effect of phytochemicals: anti-inflammatory and neuro-modulatory actions.Inflammation research : official journal of the European Histamine Research Society ... [et al.] · 2018
    Review
  14. Article
  15. Review
  16. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 1 institution in 1 country.

Bing Wu1 Department of Physiology, Medical College of Nanchang University, Nanchang, Jiangxi, People's Republic of China.
Yucheng Ma2 Queen Mary School, Medical College of Nanchang University Nanchang, Jiangxi, People's Republic of China.
Zhihua Yi1 Department of Physiology, Medical College of Nanchang University, Nanchang, Jiangxi, People's Republic of China.
Shuangmei Liu1 Department of Physiology, Medical College of Nanchang University, Nanchang, Jiangxi, People's Republic of China.
Shenqiang Rao1 Department of Physiology, Medical College of Nanchang University, Nanchang, Jiangxi, People's Republic of China.
Lifang Zou1 Department of Physiology, Medical College of Nanchang University, Nanchang, Jiangxi, People's Republic of China.
Shouyu Wang1 Department of Physiology, Medical College of Nanchang University, Nanchang, Jiangxi, People's Republic of China.
Yun Xue1 Department of Physiology, Medical College of Nanchang University, Nanchang, Jiangxi, People's Republic of China.
Tianyu Jia1 Department of Physiology, Medical College of Nanchang University, Nanchang, Jiangxi, People's Republic of China.
Shanhong Zhao1 Department of Physiology, Medical College of Nanchang University, Nanchang, Jiangxi, People's Republic of China.
Liran Shi1 Department of Physiology, Medical College of Nanchang University, Nanchang, Jiangxi, People's Republic of China.
Lin Li1 Department of Physiology, Medical College of Nanchang University, Nanchang, Jiangxi, People's Republic of China.
Huilong Yuan1 Department of Physiology, Medical College of Nanchang University, Nanchang, Jiangxi, People's Republic of China.
Shangdong Liang1 Department of Physiology, Medical College of Nanchang University, Nanchang, Jiangxi, People's Republic of China.
Nanchang University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background Chronic pain is a common symptom in human immunodeficiency virus (HIV)-1 infection/acquired immunodeficiency syndrome patients. The literature shows that the HIV envelope glycoprotein 120 (gp120) can directly cause hyperalgesia by stimulating primary sensory afferent nerves. The P2X

Indexed as

AnimalsBlotting, WesternElectrophysiologyHEK293 CellsHIV Envelope Protein gp120HumansHyperalgesiaInterleukin-10MaleNeuralgiaRatsRats, Sprague-DawleyReal-Time Polymerase Chain ReactionReceptors, Purinergic P2X7ResveratrolStilbenesgp120 protein, Human immunodeficiency virus 1HIV Envelope Protein gp120Interleukin-10Receptors, Purinergic P2X7ResveratrolStilbenesdorsal root gangliaHIV gp120-associated neuropathic painP2X7 receptorresveratrol

Identifiers

PMID28554250
PMCPMC5453631
OpenAlexW2619084210

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.