ArticleBladder (San Francisco, Calif.)2017
Effect of filling rate on cystometric parameters in young and middle aged mice.
Article in Bladder (San Francisco, Calif.), 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
12 citing papers in PubMed.
- Mirabegron nighttime versus daytime dosing for women with overactive bladder syndrome: a randomized controlled trial.Scientific reports · 2025Trial
- Spoti-find: a novel, open-source void spot assay image analysis tool.American journal of physiology. Renal physiology · 2026Article
- Sphingolipid-neutralizing molecular therapy reduces psychosine cytotoxicity in Krabbe disease.iScience · 2026Article
- Article
- Modeling bladder mechanics with 4D reconstruction of murine ex vivo bladder filling.Biomechanics and modeling in mechanobiology · 2025Article
- Reflex voiding in rat occurs at consistent bladder volume regardless of pressure or infusion rate.Neurourology and urodynamics · 2023Article
- Lack of expression of miR-29a/b1 impairs bladder function in male mice.Disease models & mechanisms · 2023Article
- Afferent nerve activity in a mouse model increases with faster bladder filling rates in vitro, but voiding behavior remains unaltered in vivo.American journal of physiology. Regulatory, integrative and comparative physiology · 2022Article
- Neurophysiological control of urinary bladder storage and voiding-functional changes through development and pathology.Pediatric nephrology (Berlin, Germany) · 2021Review
- Non-invasive assessment of urinary bladder compliance using ultrasound: first validation study based on clinical urodynamic study.Annals of translational medicine · 2021Article
- Pressure-volume analysis of rat's micturition cycles in vivo.Neurourology and urodynamics · 2020Article
- Urological complications of obesity and diabetes in males and females of three mouse models: temporal manifestations.American journal of physiology. Renal physiology · 2020Article
Corrections and comments
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Authors and funding
2 authors.
Funding
Abstract
objectivesTo investigate the effect of changing the bladder filling rate during cystometry in younger (2-3 months) and older (13-14 months) C57BL/6J male mice.
methodsCystometry was performed on mice under anesthesia. Voiding cycles were established in each mouse at a pump delivery rate of 17 μl/min. After 30 min, the rate was increased sequentially to 25, 33, 41 and 49 μl/min. Each rate was maintained for 30 min. The following cystometric parameters were quantified: peak pressure amplitude, intercontractile interval (ICI), compliance, micturition pressure threshold and voiding efficiency.
resultsBladder weights were significantly greater in older mice (42 mg
conclusionsThe rate of volume delivery has complex effects on the timing of voiding and compliance. These findings argue for greater standardization of cystometry protocols and further investigation into afferent signaling to higher centers at different filling rates.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.