Evidence map›Paper›PMID 28553545›Full record

ArticleWomen's midlife health2015

Rheumatic autoimmune diseases in women and midlife health.

Wendy Marder, Évelyne Vinet, Emily C Somers

Open access · goldAbstract read
In one paragraph

Article in Women's midlife health, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.

0numbers the graph read from it
0cells of the map it votes in
27citing papers in PubMed
8.6field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

27 citing papers in PubMed, 74 citations in OpenAlex.

  1. Article
  2. Article
  3. Sex Bias in Autoimmunity: New Findings and New Opportunities.JID innovations : skin science from molecules to population health · 2025
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 2 countries.

Wendy MarderDivision of Rheumatology, Department of Internal Medicine, University of Michigan, Ann Arbor, MI, USA.
Évelyne VinetDivision of Rheumatology, McGill University Health Centre, Montreal, Canada.
Emily C SomersDivision of Rheumatology, Department of Internal Medicine, University of Michigan, Ann Arbor, MI, USA.
University of Michigan–Ann Arbor · USMcGill University Health Centre · CA

Funding

Michigan BIRCWH Career Development ProgramK12HD001438 · NICHD · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI JOHNSON, TIMOTHY RB · 2000 to 2014
$6.7M
Michigan Lupus Epidemiology & Surveillance (MILES) Program Longitudinal CohortU01DP003250 · DP · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI SOMERS, EMILY CATHERINE · 2012 to 2015
$3.0M
Immune dysfunction associated with early life heavy metal exposureK01ES019909 · NIEHS · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI SOMERS, EMILY CATHERINE · 2011 to 2015
$670k
NCCDPHP CDC HHS U01 DP003250NCCDPHP CDC HHS U01 DP006265NICHD NIH HHS K12 HD001438NIEHS NIH HHS K01 ES019909
6 · The paper itself

Abstract

Autoimmune diseases such as systemic lupus erythematosus (SLE), rheumatoid arthritis (RA), and systemic sclerosis (scleroderma) preferentially affect women, and are characterized by systemic inflammation leading to target organ dysfunction. The public health burden of autoimmune diseases, which collectively represent a leading cause of morbidity and mortality among women throughout adulthood, is substantial. While some features of these diseases have been observed to improve over the menopausal transition, such as disease flare rate in SLE and skin softening and thinning in scleroderma, others, such as swollen and tender joints and radiographically confirmed damage in RA may worsen. The general trends, however, are not consistent or conclusive for all disease-related manifestations. Of great importance is the recognition that comorbid diseases, including osteoporosis and accelerated cardiovascular disease, contribute excess morbidity and mortality that becomes increasingly apparent as women with autoimmune diseases undergo the menopausal transition.

Indexed as

Autoimmune diseasesRheumatic diseasesRheumatoid arthritisSclerodermaSystemic lupus erythematosus

Identifiers

PMID28553545
PMCPMC5444314
OpenAlexW2196477454

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.