Evidence map›Paper›PMID 28553544›Full record

ArticleJournal of cancer research & therapy2013

Development of novel approach to diagnostic imaging of lung cancer with

V Galitovskiy, S A Kuruvilla, E Sevriokov, A Corches, M L Pan, M Kalantari-Dehaghi, A I Chernyavsky, J Mukherjee, S A Grando

Open access · hybridAbstract read
In one paragraph

Article in Journal of cancer research & therapy, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
0.8field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 12 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

V GalitovskiyDepartment of Dermatology, University of California-Irvine, Irvine, CA 92697, USA.
S A KuruvillaPreclinical Imaging, Department of Radiological Sciences, University of California-Irvine, Irvine, CA 92697, USA.
E SevriokovPreclinical Imaging, Department of Radiological Sciences, University of California-Irvine, Irvine, CA 92697, USA.
A CorchesPreclinical Imaging, Department of Radiological Sciences, University of California-Irvine, Irvine, CA 92697, USA.
M L PanPreclinical Imaging, Department of Radiological Sciences, University of California-Irvine, Irvine, CA 92697, USA.
M Kalantari-DehaghiDepartment of Dermatology, University of California-Irvine, Irvine, CA 92697, USA.
A I ChernyavskyDepartment of Dermatology, University of California-Irvine, Irvine, CA 92697, USA.
J MukherjeePreclinical Imaging, Department of Radiological Sciences, University of California-Irvine, Irvine, CA 92697, USA.
S A GrandoDepartment of Dermatology, University of California-Irvine, Irvine, CA 92697, USA.
University of California, Irvine · US

Funding

PET Imaging Agents for Nicotinic a4b2 ReceptorsR01AG029479 · NIA · UNIVERSITY OF CALIFORNIA-IRVINE · PI MUKHERJEE, JOGESHWAR · 2007 to 2017
$2.6M
Nicotinic Receptor Ligands and Tobacco-induced Lung CancerR01ES017009 · NIEHS · UNIVERSITY OF CALIFORNIA-IRVINE · PI GRANDO, SERGEI A · 2010 to 2014
$1.7M
Small Animal MicroCTS10RR024546 · NCRR · UNIVERSITY OF CALIFORNIA-IRVINE · PI MUKHERJEE, JOGESHWAR · 2009 to 2009
$431k
NCRR NIH HHS S10 RR024546NIA NIH HHS R01 AG029479NIEHS NIH HHS R01 ES017009
6 · The paper itself

Abstract

Development of novel methods of early diagnosis of lung cancer is one of the major tasks of contemporary clinical and experimental oncology. In this study, we utilized the tobacco nitrosamine 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK)-induced lung cancer in A/J mice as an animal model for development of a new imaging technique for early diagnosis of lung cancer. Lung cancer cells in A/J mice overexpress nicotinic acetylcholine receptors. Longitudinal CT scans were carried out over a period of 8 months after NNK treatment, followed by PET/CT scans with

Indexed as

18F-FDG18F-NifeneA/J micelung cancernicotinic receptorsNNKPET/CT imaging

Identifiers

PMID28553544
PMCPMC5443253
OpenAlexW2334867674

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.