ArticleChemical science2017
Long wavelength excitable near-infrared fluorescent nanoparticles with aggregation-induced emission characteristics for image-guided tumor resection.
Article in Chemical science, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 35 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
35 citing papers in PubMed, 181 citations in OpenAlex.
- Spatially Confined/Ligand-Directed Ultrabright NIR-AIE Nanoprobe for In Vitro Rapid Detection and In Situ Imaging of Bacterial Septic Arthritis.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026Article
- The reproductive toxicity of aggregation-induced emission nanoparticles on mouse ovarian function.iScience · 2026Article
- Synthesis of Upconversion Nanoparticles with Manipulable Crystal Phase, Size Specification, and Morphological Features.Journal of fluorescence · 2025Article
- Transformative bioprinting: 4D printing and its role in the evolution of engineering and personalized medicine.Discover nano · 2025Review
- Smart molecular probes with controllable photophysical property for smart medicine.Smart molecules : open access · 2024Review
- Gold Nanoclusters as High Resolution NIR-II Theranostic Agents.Chemical & biomedical imaging · 2024Review
- Excited-State Conjugation/De-Conjugation Driven Nonradiative Thermal Deactivation for Developing Fluorogenic Probes to Diagnose Cancers.Chemical & biomedical imaging · 2024Article
- A planar electronic acceptor motif contributing to NIR-II AIEgen with combined imaging and therapeutic applications.Chemical science · 2024Article
- Internalization of Pegylated Er:YACS applied nano materials · 2023Article
- Aggregation-Induced Emission (AIE), Life and Health.ACS nano · 2023Review
- Detection of breast cancer cells by a near-infrared fluorescent probe targeting mitochondrial viscosity.Heliyon · 2023Article
- Polymersomes Based Versatile Nanoplatforms for Controlled Drug Delivery and Imaging.Advanced pharmaceutical bulletin · 2023Review
- Fluorescent Nanoparticles for Super-Resolution Imaging.Chemical reviews · 2022Review
- Acceptor engineering for NIR-II dyes with high photochemical and biomedical performance.Nature communications · 2022Article
- Review
- Imaging, Identification and Inhibition of Microorganisms Using AIEgens.Topics in current chemistry (Cham) · 2021Review
- Fluorescent small organic probes for biosensing.Chemical science · 2021Review
- Recent Advances in Second Near-Infrared Region (NIR-II) Fluorophores and Biomedical Applications.Frontiers in chemistry · 2021Review
- Article
- Tuning molecular aggregation to achieve highly bright AIE dots for NIR-II fluorescence imaging and NIR-I photoacoustic imaging.Chemical science · 2020Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Near infrared (NIR) fluorescence imaging (700-900 nm) is a promising technology in preclinical and clinical tumor diagnosis and therapy. The availability of excellent NIR fluorescent contrast agents is still the main barrier to implementing this technology. Herein, we report the design and synthesis of two series of NIR fluorescent molecules with long wavelength excitation and aggregation-induced emission (AIE) characteristics by fine-tuning their molecular structures and substituents. Further self-assembly between an amphiphilic block co-polymer and the obtained AIE molecules leads to AIE nanoparticles (AIE NPs), which have absorption maxima at 635 nm and emission maxima between 800 and 815 nm with quantum yields of up to 4.8% in aggregated states.
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.