Evidence map›Paper›PMID 28553472›Full record

ArticleChemical science2015

Chelate-free metal ion binding and heat-induced radiolabeling of iron oxide nanoparticles.

Eszter Boros, Alice M Bowen, Lee Josephson, Neil Vasdev, Jason P Holland

Open access · hybridAbstract read
In one paragraph

Article in Chemical science, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 50 papers.

0numbers the graph read from it
0cells of the map it votes in
50citing papers in PubMed
10.5field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

50 citing papers in PubMed, 120 citations in OpenAlex.

  1. Article
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  12. Article
  13. Nanomaterials (Basel, Switzerland) · 2022
    Article
  14. Review
  15. Imaging Constructs: The Rise of Iron Oxide Nanoparticles.Molecules (Basel, Switzerland) · 2021
    Review
  16. Review
  17. Radiolabeling of Theranostic Nanosystems.Advances in experimental medicine and biology · 2021
    Article
  18. Article
  19. Article
  20. Applied organometallic chemistry · 2020
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 5 institutions in 3 countries.

Eszter BorosThe Athinoula A. Martinos Center for Biomedical Imaging , 149 13th Street, Suite 2301 , Charlestown , Massachusetts 02129 , USA.
Alice M BowenCenter for Biomolecular Magnetic Resonance (BMRZ) , Institute of Physical and Theoretical Chemistry , Goethe University Frankfurt , Max-von-Laue-Str. 7, Building N140/Ground Floor , 60438 Frankfurt am Main , Germany.
Lee JosephsonCenter for Advanced Molecular Imaging Sciences , Massachusetts General Hospital , Harvard Medical School , 149 13th Street , Charlestown , Massachusetts 02129 , USA.
Neil VasdevDepartment of Radiology , Massachusetts General Hospital , Harvard Medical School , 55 Fruit Street , Boston , Massachusetts 02114 , USA . Email: holland.jason@mgh.harvard.edu ; Email: jasonpholland@gmail.com ; ; Tel: +1-617-726-6107.
Jason P HollandDepartment of Radiology , Massachusetts General Hospital , Harvard Medical School , 55 Fruit Street , Boston , Massachusetts 02114 , USA . Email: holland.jason@mgh.harvard.edu ; Email: jasonpholland@gmail.com ; ; Tel: +1-617-726-6107.
Advanced Imaging Research (United States) · USAthinoula A. Martinos Center for Biomedical Imaging · USGoethe University Frankfurt · DEHarvard University · USMassachusetts General Hospital · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A novel reaction for chelate-free, heat-induced metal ion binding and radiolabeling of ultra-small paramagnetic iron oxide nanoparticles (USPIOs) has been established. Radiochemical and non-radioactive labeling studies demonstrated that the reaction has a wide chemical scope and is applicable to p-, d- and f-block metal ions with varying ionic sizes and formal oxidation states from 2+ to 4+. Radiolabeling studies found that

Identifiers

PMID28553472
PMCPMC5433050
OpenAlexW2150943897

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.