Evidence map›Paper›PMID 28553471›Full record

ArticleChemical science2015

An organometallic structure-activity relationship study reveals the essential role of a Re(CO)

Malay Patra, Michaela Wenzel, Pascal Prochnow, Vanessa Pierroz, Gilles Gasser, Julia E Bandow, Nils Metzler-Nolte

Open access · hybridAbstract read
In one paragraph

Article in Chemical science, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed
5.1field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 80 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Review
  10. Metals to combat antimicrobial resistance.Nature reviews. Chemistry · 2023
    Review
  11. Article
  12. Article
  13. Review
  14. Review
  15. Article
  16. Article
  17. Article
  18. Article
  19. Light-Activated Rhenium Complexes with Dual Mode of Action against Bacteria.Chemistry (Weinheim an der Bergstrasse, Germany) · 2020
    Article
  20. Metal Complexes, an Untapped Source of Antibiotic Potential?Antibiotics (Basel, Switzerland) · 2020
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 2 countries.

Malay PatraLehrstuhl für Anorganische Chemie I - Bioanorganische Chemie , Fakultät für Chemie und Biochemie , Ruhr-Universität Bochum , Universitätsstrasse 150 , D-44801 Bochum , Germany . Email: Nils.Metzler-Nolte@rub.de.
Michaela WenzelRuhr-Universität Bochum , Biologie der Mikroorganismen , Arbeitsgruppe Mikrobielle Antibiotikaforschung , Universitätsstrasse 150 , D-44801 Bochum , Germany . Email: julia.bandow@rub.de ; ; Tel: +49-234-32-23102.
Pascal ProchnowRuhr-Universität Bochum , Biologie der Mikroorganismen , Arbeitsgruppe Mikrobielle Antibiotikaforschung , Universitätsstrasse 150 , D-44801 Bochum , Germany . Email: julia.bandow@rub.de ; ; Tel: +49-234-32-23102.
Vanessa PierrozDepartment of Chemistry , University of Zurich , Winterthurerstrasse 190 , CH-8057 Zurich , Switzerland.
Gilles GasserDepartment of Chemistry , University of Zurich , Winterthurerstrasse 190 , CH-8057 Zurich , Switzerland.
Julia E BandowRuhr-Universität Bochum , Biologie der Mikroorganismen , Arbeitsgruppe Mikrobielle Antibiotikaforschung , Universitätsstrasse 150 , D-44801 Bochum , Germany . Email: julia.bandow@rub.de ; ; Tel: +49-234-32-23102.
Nils Metzler-NolteLehrstuhl für Anorganische Chemie I - Bioanorganische Chemie , Fakultät für Chemie und Biochemie , Ruhr-Universität Bochum , Universitätsstrasse 150 , D-44801 Bochum , Germany . Email: Nils.Metzler-Nolte@rub.de.
Ruhr University Bochum · DEUniversity of Zurich · CH

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The worrying appearance of microbial resistance to antibiotics is a worldwide problem which needs to be tackled urgently. Microbial resistance to the common classes of antibiotics involving purely organic compounds unfortunately develops very rapidly and in most cases, resistance was detected soon after or even before release of the antibiotic to the market. Therefore, novel concepts for antibiotics must be investigated, and metal-containing compounds hold particular promise in that area. Taking a trimetallic complex (

Identifiers

PMID28553471
PMCPMC5433042
OpenAlexW2142664741

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.