ArticleThe open neuroimaging journal2017
Functional Evaluation of Awareness in Vegetative and Minimally Conscious State.
Article in The open neuroimaging journal, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 1 of them a synthesis that pooled it.
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The trial behind it
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Who cites it
17 citing papers in PubMed, 1 synthesis or guideline pooled it, 23 citations in OpenAlex.
- Meta-analysis of the diagnostic value of functional magnetic resonance imaging for distinguishing unresponsive wakefulness syndrome/vegetative state and minimally conscious state.Frontiers in neuroscience · 2024Pooled it
- Intrinsic Brain Activity Alterations in Disorders of Consciousness: A Parallel Resting-State fMRI Analysis at 7 Tesla.Brain topography · 2026Article
- EEG oscillatory changes following rehabilitative tactile and thermal stimulation in disorders of consciousness: a longitudinal and pilot study.Frontiers in neuroscience · 2026Article
- Functional connectivity in whole-brain and network analysis differentiates minimally conscious from unresponsive patients: a resting-state fNIRS study.Journal of translational medicine · 2025Article
- Prognostic Evaluation of Disorders of Consciousness by Using Resting-State fMRI: A Systematic Review.Journal of clinical medicine · 2024Review
- Functional PET Neuroimaging in Consciousness Evaluation: Study Protocol.Diagnostics (Basel, Switzerland) · 2023Article
- Relationship between Coma Recovery Scale-Revised and the Thalamocortical Tract of Ascending Reticular Activating System in Hypoxic-Ischemic Brain Injury: A Pilot Study.Healthcare (Basel, Switzerland) · 2023Article
- Use of magnetic source imaging to assess recovery after severe traumatic brain injury-an MEG pilot study.Frontiers in neurology · 2023Article
- Role of neurorehabilitative treatment using transcranial magnetic stimulation in disorders of consciousness.The Journal of international medical research · 2021Review
- The Potential Role of fNIRS in Evaluating Levels of Consciousness.Frontiers in human neuroscience · 2021Article
- Diagnostic Developments in Differentiating Unresponsive Wakefulness Syndrome and the Minimally Conscious State.Frontiers in neurology · 2021Review
- The impact of the SARS-COV2 infection on the disorder of consciousness rehabilitation unit.PloS one · 2021Article
- Network Mapping of Connectivity Alterations in Disorder of Consciousness: Towards Targeted Neuromodulation.Journal of clinical medicine · 2020Article
- Is the "Minimally Conscious State" Patient Minimally Self-Aware?Frontiers in psychology · 2020Review
- Human Computer Interface for Tracking Eye Movements Improves Assessment and Diagnosis of Patients With Acquired Brain Injuries.Frontiers in neurology · 2019Article
- Measures of CNS-Autonomic Interaction and Responsiveness in Disorder of Consciousness.Frontiers in neuroscience · 2019Review
- A Systematic Review and Meta-Analysis of the Relationship Between Brain Data and the Outcome in Disorders of Consciousness.Frontiers in neurology · 2018Article
Corrections and comments
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Authors and funding
10 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveThe aim of this study was to assess differences in brain activation in a large sample of Vegetative State (VS) and Minimally Conscious State (MCS) patients, using functional magnetic resonance imaging (fMRI).
methodsWe studied 50 patients four to seven months after brain injury. By using international clinical criteria and validated behavioural scales such as the Glasgow Coma Scale and the Clinical Unawareness Assessment Scale, the patients were grouped into
resultsfMRI showed significant (p<0.01, cluster-corrected) brain activation in the primary auditory cortex bilaterally during the acoustic stimuli in patients with both VS and MCS. However, ten patients clinically classified as VS, showed a pattern of brain activation very similar to that of MCS patients. Six months later, these ten VS patients had significant clinical improvement, evolving into MCS, whereas the other VS patients and patients with MCS remained clinically stable.
conclusionBrain activity could help in discerning whether the status of wakefulness in
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.