ArticleJournal of smoking cessation2017
Sleep Disturbance During Smoking Cessation: Withdrawal or Side Effect of Treatment?
Article in Journal of smoking cessation, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
26 citing papers in PubMed, 1 synthesis or guideline pooled it, 42 citations in OpenAlex.
- Nicotine receptor partial agonists for smoking cessation.The Cochrane database of systematic reviews · 2023Pooled it
- Sleep Difficulties and Their Associations With Smoking Abstinence Among Adults Seeking Tobacco Cessation Treatment.American journal of preventive medicine · 2026Article
- Association of Healthy Lifestyle with Insomnia Among Chinese Older Adults: A Cross-Sectional Study.Clocks & sleep · 2026Article
- Pilot trial of delayed versus immediate financial incentives for smoking cessation.Contemporary clinical trials communications · 2026Article
- Evaluating the impact of a tobacco tax increase on smoking cessation outcomes: A seven-year retrospective study from a regional teaching hospital in Taiwan.AIMS public health · 2026Article
- Motivation meets sleep: tuning arousal via nucleus accumbens and Basal Ganglia circuits.Npj biological timing and sleep · 2025Review
- Investigation and analysis of factors related to sleep conditions during the acute withdrawal period of alcohol use disorder.Frontiers in psychiatry · 2025Article
- Repeated participation in hospital smoking cessation services and its effectiveness in smoking cessation: a seven-year observational study in Taiwan.Archives of public health = Archives belges de sante publique · 2024Article
- The potential of AB-free kava in enabling tobacco cessation via management of abstinence-related stress and insomnia: study protocol for a randomized clinical trial.BMC complementary medicine and therapies · 2024Article
- Flavokavains A- and B-Free Kava Enhances Resilience against the Adverse Health Effects of Tobacco Smoke in Mice.ACS pharmacology & translational science · 2024Article
- Disrupted Circadian Rhythms and Substance Use Disorders: A Narrative Review.Clocks & sleep · 2024Review
- The Interactions between Smoking and Sleep.Biomedicines · 2024Review
- Associations Between Self-Reported Sleep Quality, Fatigue Severity, Factors Associated With Successful Cessation, and Cessation Beliefs Among Regular Smokers.Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco · 2024Observational
- Discrimination and insomnia: Examining depressive symptoms and nicotine withdrawal through a serial mediation model in a sample of smokers.Addictive behaviors · 2023Article
- Characterization of Ultrapotent Chemogenetic Ligands for Research Applications in Nonhuman Primates.ACS chemical neuroscience · 2022Article
- Dual Orexin Receptor Antagonists (DORAs) as an Adjunct Treatment for Smoking Cessation.CNS drugs · 2022Article
- Article
- Risk of neuropsychiatric adverse events associated with varenicline treatment for smoking cessation among Dutch population: A sequence symmetry analysis.Pharmacoepidemiology and drug safety · 2022Article
- Can exercise alleviate sleep disturbances during acute nicotine withdrawal in cigarette smokers?Experimental and clinical psychopharmacology · 2022Article
- The experience of tobacco withdrawal symptoms among current smokers and ex-smokers in the general population: Findings from nationwide China Health Literacy Survey during 2018-19.Frontiers in psychiatry · 2022Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors at 5 institutions in 2 countries.
Funding
Abstract
introductionThe nicotine-metabolite ratio (NMR) predicts treatment response and is related to treatment side effect severity. Sleep disturbance may be one important side effect, but understanding sleep disturbance effects on smoking cessation is complicated by the fact that nicotine withdrawal also produces sleep disturbance.
aimsTo evaluate the effects of withdrawal and treatment side effects on sleep disturbance.
methodsThis is a secondary analysis of data from a clinical trial (Lerman et al., 2015) of 1,136 smokers randomised to placebo (
resultsThe varenicline and TN groups exhibited greater increases in sleep disturbance (vs. placebo; treatment × time interaction;
conclusionsExisting treatments may not mitigate withdrawal-related sleep disturbance and adjunctive treatments that target sleep disturbance may improve abstinence rates.
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.