Evidence map›Paper›PMID 28553341›Full record

ArticleNeural regeneration research2017

Diffusion tensor imaging assesses white matter injury in neonates with hypoxic-ischemic encephalopathy.

Hong-Xin Li, Xing Feng, Qian Wang, Xuan Dong, Min Yu, Wen-Juan Tu

Open access · goldAbstract read
In one paragraph

Article in Neural regeneration research, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
2.0field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 25 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 4 institutions in 1 country.

Hong-Xin LiDepartment of Neonatology, Children's Hospital of Soochow University, Suzhou, Jiangsu Province, China.
Xing FengDepartment of Neonatology, Children's Hospital of Soochow University, Suzhou, Jiangsu Province, China.ORCID 0000-0003-0519-3780
Qian WangSchool of Biomedical Engineering, Shanghai Jiao Tong University, Shanghai, China.
Xuan DongDepartment of Children's Health Research Center, Changzhou Children's Hospital, Changzhou, Jiangsu Province, China.
Min YuNantong University, Nantong, Jiangsu Province, China.
Wen-Juan TuDepartment of Neonatology, Changzhou Children's Hospital, Changzhou, Jiangsu Province, China.
Hangzhou Children's Hospital · CNNantong University · CNShanghai Jiao Tong University · CNSoochow University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

With improvements in care of at-risk neonates, more and more children survive. This makes it increasingly important to assess, soon after birth, the prognosis of children with hypoxic-ischemic encephalopathy. Computed tomography, ultrasound, and conventional magnetic resonance imaging are helpful to diagnose brain injury, but cannot quantify white matter damage. In this study, ten full-term infants without brain injury and twenty-two full-term neonates with hypoxic-ischemic encephalopathy (14 moderate cases and 8 severe cases) underwent diffusion tensor imaging to assess its feasibility in evaluating white matter damage in this condition. Results demonstrated that fractional anisotropy, voxel volume, and number of fiber bundles were different in some brain areas between infants with brain injury and those without brain injury. The correlation between fractional anisotropy values and neonatal behavioral neurological assessment scores was closest in the posterior limbs of the internal capsule. We conclude that diffusion tensor imaging can quantify white matter injury in neonates with hypoxic-ischemic encephalopathy.

Indexed as

apparent diffusion coefficientbrain injurydiffusion tensor imagingfractional anisotropyneonatal behavioral neurological assessmentnerve regenerationneural regenerationneuroimagingvoxel volumewhite matter

Identifiers

PMID28553341
PMCPMC5436359
OpenAlexW2609772225

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.