Evidence map›Paper›PMID 28553080›Full record

ReviewDrug design, development and therapy2017

Ten years of clinical experience with biosimilar human growth hormone: a review of safety data.

Maria Victoria Borrás Pérez, Berit Kriström, Tomasz Romer, Mieczyslaw Walczak, Nadja Höbel, Markus Zabransky

Open access · goldAbstract readComparative StudyReview
In one paragraph

Review in Drug design, development and therapy, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.8field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 23 citations in OpenAlex.

  1. Observational
  2. Observational
  3. Review
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 5 institutions in 5 countries.

Maria Victoria Borrás PérezHospital General de Granollers, Granollers, Barcelona, Spain.
Berit KriströmDepartment of Clinical Sciences, Pediatrics, Umeå University, Umeå, Sweden.
Tomasz RomerDepartment of Endocrinology, Children's Health Research Institute, Warsaw.
Mieczyslaw WalczakDepartment of Paediatric Endocrinology and Diabetology, Pomeranian Medical University, Szczecin, Poland.
Nadja HöbelSandoz Biopharmaceuticals, Hexal AG, Holzkirchen, Germany.
Markus ZabranskySandoz Biopharmaceuticals, Hexal AG, Holzkirchen, Germany.
Hexal (Germany) · DEChildren’s Health Research Institute · CAHospital General de Granollers · ESPomeranian Medical University · PLUmeå University · SE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Safety concerns for recombinant human growth hormone (rhGH) treatments include impact on cancer risk, impact on glucose homeostasis, and the formation of antibodies to endogenous/exogenous GH. Omnitrope

Indexed as

Drug ApprovalBiosimilar PharmaceuticalsEuropeHuman Growth HormoneHumansRecombinant ProteinsBiosimilar PharmaceuticalsHuman Growth HormoneRecombinant ProteinsbiosimilarOmnitrope®recombinant human growth hormone

Identifiers

PMID28553080
PMCPMC5439985
OpenAlexW2616264501

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.