ArticlePLoS neglected tropical diseases2017
Optimising cluster survey design for planning schistosomiasis preventive chemotherapy.
Article in PLoS neglected tropical diseases, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers, 2 of them syntheses that pooled it.
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Who cites it
25 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Association of schistosomiasis and HIV infections: A systematic review and meta-analysis.International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases · 2021Pooled it
- Systematic review of community-based, school-based, and combined delivery modes for reaching school-aged children in mass drug administration programs for schistosomiasis.PLoS neglected tropical diseases · 2017Pooled it
- Assessing the benefits of five years of different approaches to treatment of urogenital schistosomiasis: A SCORE project in Northern Mozambique.PLoS neglected tropical diseases · 2017Trial
- Spatial distribution of urogenital schistosomiasis in school-aged children in Togo: an oversampling survey in three districts in 2022.Parasites & vectors · 2026Article
- Revisiting the epidemiology of schistosomiasis and soil-transmitted helminthiasis in Chad: insights for improved interventions.International health · 2025Article
- Piloting the Schistosomiasis Practical and Precision Assessment approach in five health districts of the N'zérékoré region, Republic of Guinea.PLoS neglected tropical diseases · 2025Article
- Sensitivity of Three Impact Assessment Methodologies in Adjusting Preventive Chemotherapy Treatment Decisions for Schistosomiasis Elimination in Ondo State, Nigeria.The American journal of tropical medicine and hygiene · 2025Article
- The impact and cost of a new rapid diagnostic test for school-based prevalence mapping and monitoring and evaluation surveys of schistosomiasis: A modelling study.PLoS neglected tropical diseases · 2025Article
- Prevalence, intensity and risk factors of soil-transmitted helminthiasis after five effective rounds of preventive chemotherapy across three implementation units in Ondo State, Nigeria.PLoS neglected tropical diseases · 2025Article
- Schistosomiasis in Ghana from baseline to now: the impact of fifteen years of interventions.Frontiers in public health · 2025Article
- Cost-effectiveness of comparative survey designs for helminth control programs: Post-hoc cost analysis and modelling of the Kenyan national school-based deworming program.PLoS neglected tropical diseases · 2024Article
- Effectiveness of Three Sampling Approaches for Optimizing Mapping and Preventive Chemotherapy againstTropical medicine and infectious disease · 2024Article
- Re-assessment of schistosomiasis in nine endemic districts with cluster sampling in Sierra Leone.Frontiers in public health · 2024Article
- Progress from morbidity control to elimination as a public health problem of schistosomiasis and the status of soil-transmitted helminth infection in Togo: a second impact assessment after ten rounds of mass drug administration.Parasites & vectors · 2023Article
- School-based preventive chemotherapy program for schistosomiasis and soil-transmitted helminth control in Angola: 6-year impact assessment.PLoS neglected tropical diseases · 2023Article
- Combining school-catchment area models with geostatistical models for analysing school survey data from low-resource settings: Inferential benefits and limitations.Spatial statistics · 2022Article
- A cost-analysis of conducting population-based prevalence surveys for the validation of the elimination of trachoma as a public health problem in Amhara, Ethiopia.PLoS neglected tropical diseases · 2020Article
- Contributions of the Schistosomiasis Consortium for Operational Research and Evaluation (SCORE) to Schistosomiasis Control and Elimination: Key Findings and Messages for Future Goals, Thresholds, and Operational Research.The American journal of tropical medicine and hygiene · 2020Review
- Achieving Elimination as a Public Health Problem for Schistosoma mansoni and S. haematobium: When Is Community-Wide Treatment Required?The Journal of infectious diseases · 2020Article
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Corrections and comments
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Authors and funding
17 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThe cornerstone of current schistosomiasis control programmes is delivery of praziquantel to at-risk populations. Such preventive chemotherapy requires accurate information on the geographic distribution of infection, yet the performance of alternative survey designs for estimating prevalence and converting this into treatment decisions has not been thoroughly evaluated. METHODOLOGY/PRINCIPAL
findingsWe used baseline schistosomiasis mapping surveys from three countries (Malawi, Côte d'Ivoire and Liberia) to generate spatially realistic gold standard datasets, against which we tested alternative two-stage cluster survey designs. We assessed how sampling different numbers of schools per district (2-20) and children per school (10-50) influences the accuracy of prevalence estimates and treatment class assignment, and we compared survey cost-efficiency using data from Malawi. Due to the focal nature of schistosomiasis, up to 53% simulated surveys involving 2-5 schools per district failed to detect schistosomiasis in low endemicity areas (1-10% prevalence). Increasing the number of schools surveyed per district improved treatment class assignment far more than increasing the number of children sampled per school. For Malawi, surveys of 15 schools per district and 20-30 children per school reliably detected endemic schistosomiasis and maximised cost-efficiency. In sensitivity analyses where treatment costs and the country considered were varied, optimal survey size was remarkably consistent, with cost-efficiency maximised at 15-20 schools per district. CONCLUSIONS/SIGNIFICANCE: Among two-stage cluster surveys for schistosomiasis, our simulations indicated that surveying 15-20 schools per district and 20-30 children per school optimised cost-efficiency and minimised the risk of under-treatment, with surveys involving more schools of greater cost-efficiency as treatment costs rose.
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