Evidence map›Paper›PMID 28552468›Full record

ArticleAnnals of epidemiology2017

Air pollution and cardiovascular events at labor and delivery: a case-crossover analysis.

Sandie Ha, Tuija Männistö, Danping Liu, Seth Sherman, Qi Ying, Pauline Mendola

Abstract read
In one paragraph

Article in Annals of epidemiology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Review
  4. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

6 authors.

Sandie HaEpidemiology Branch, Division of Intramural Population Health Research, NICHD, Bethesda, MD.
Tuija MännistöNorthern Finland Laboratory Centre NordLab, Oulu, Finland; Department of Clinical Chemistry, University of Oulu, Oulu, Finland; Medical Research Center Oulu, Oulu University Hospital and University of Oulu, Oulu, Finland; National Institute for Health and Welfare, Oulu, Finland.
Danping LiuBiostatistics and Bioinformatics Branch, Division of Intramural Population Health Research, NICHD, Bethesda, MD.
Seth ShermanThe Emmes Corporation, Rockville, MD.
Qi YingTexas A&M University, Zachry Department of Civil Engineering, College Station, TX.
Pauline MendolaEpidemiology Branch, Division of Intramural Population Health Research, NICHD, Bethesda, MD. Electronic address: pauline.mendola@nih.gov.

Funding

Consortium on Safe LaborZIAHD008794 · NICHD · EUNICE KENNEDY SHRIVER NATIONAL INSTITUTE OF CHILD HEALTH & HUMAN DEVELOPMENT · PI GRANTZ, KATHERINE · 2009 to 2022
$3.2M
Air Quality and Reproductive HealthZIAHD008923 · NICHD · EUNICE KENNEDY SHRIVER NATIONAL INSTITUTE OF CHILD HEALTH & HUMAN DEVELOPMENT · PI MENDOLA, PAULINE · 2012 to 2020
$3.2M
Intramural NIH HHS Z99 HD999999Intramural NIH HHS ZIA HD008794Intramural NIH HHS ZIA HD008923NICHD NIH HHS HHSN267200603425CNICHD NIH HHS HHSN275200800002CNICHD NIH HHS HHSN275200800002I
6 · The paper itself

Abstract

purposeIn this case-crossover study, we investigated the odds of having a labor/delivery with cardiovascular event (i.e., ischemic heart disease, stroke, heart failure, cardiac arrest/failure, and other or unspecified cardiovascular events) associated with acute exposure to common air pollutants.

methodsWe selected 680 women with singleton pregnancy and cardiovascular events at labor/delivery from 12 U.S. clinical sites (2002-2008). Exposures to six criteria air pollutants, six particulate constituents, and 26 air toxics were obtained using modified Community Multiscale Air Quality models. Conditional logistic regression models calculated the odds ratio (OR) and 95% confidence intervals (CI) comparing exposures during the day of delivery, the week before delivery, and each of the days of the week before delivery to two control periods before and after.

resultsAn interquartile range increase in particulate matter (PM) ≤2.5 microns and nitric oxide exposures during the week before delivery was associated with an 11% (OR 1.11, 95% CI: 1.01-1.23) and 21% (OR 1.21, 95% CI: 1.04-1.42) increased cardiovascular events odds, respectively. These pollutants, sulfur dioxide, carbon monoxide, PM ≤ 10 microns, and some PM constituents showed associations with event odds for days 0, 1, 5, and 6 before delivery. Inverse associations were observed for O

conclusionsCardiovascular events at labor/delivery merit more attention in relation to air pollution.

Indexed as

Delivery, ObstetricEnvironmental ExposureLabor, ObstetricAdultAir PollutantsAir PollutionCarbon MonoxideCardiovascular DiseasesCross-Over StudiesFemaleHeart ArrestHeart FailureHumansNitric OxideParticulate MatterParturitionAir PollutantsCarbon MonoxideNitric OxideParticulate MatterSulfur DioxideAir pollutionCardiovascular eventsLabor and deliveryPregnancy

Identifiers

PMID28552468
PMCPMC5533083

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.